Position
| Chromosome | chr21 |
| Start | 537604 |
| End | 539645 |
| Strand | + |
view in Gbrowse: chr21:537604..539645
Most similar sequence in NCBI nr database
| Accession | Description | E-value | Score |
|---|---|---|---|
| BAM73889.1 | cytochrome P450 | 0.0 | 1053 |
ORF sequence (1536 bp)
ATGCTCACCGCCGCGATATTCGTTATCATTGTCGCTCTTGTTTATTTGTACTCAACTAGAACGTTCAGATACTGGGAGAAAAGGGGCATCAAACATGATAAGCCTGTACCCTTCTTCGGCACCGATTCAGAGGGATATCTACTCAGAAAAAGCATGACCCAAACTGCTGTGGATGCATATCTCAAATACCCCAATGAAAAAGTCATCGGTTTCTTCAGATCCTCAAGGCCTGAACTAATCATCAGAGACCCGGATATTATAAAACGAATTCTAACAACAGACTTCGCGTATTTCTATCCAAGGGGACTGAATCCACATAAAAAGGTAATTGAGCCGTTGATGCGTAACCTGTTTTTCGCTGATGGGGATCTGTGGCGTCTTCTACGTCAACGTATGACACCTGCATTTACCAGCGGGAAATTGCGTGCCATGTTTCCTCTGGTCGTGGAAAGAGCTGAAAGACTTCAATCTCGGACCCTTGAGATTGCTTCACAACCTCTAGATGCTAGAGAACTAATGGCACGTTACACGACAGATTTCATAGGCGCTTGCGGCTTTGGCCTCGATGCAGACTCACTGAACGACGAAGATTCAGCATTCAGAAAGCTTGGAGCGGCCATTTTCAACATAACTGTTCAGCAAGCAATCGTGGCTGCCCTCAAAGAGATATTCCCTGGGATATTCAAGCATTTTAAGTACTCATCGAAGTATGAAACAGATTTTATGAGTTTGGTCAGTTCCATATTAAAACAAAGAAATTACAAACCATCTGGTCGAAACGATTTTATTGATTTACTCCTCGAGTGTAGAATGAAAGGAGAAATCGTAGTGGAATCTATTGAGAAAATGAAACCAGATGGCACTTCTGAAGTCGTTAGAATGGAGTTAACAGAACAACTGCTAGCAGCTCAAGTATTCATCTTCTTTGCAGCTGGCTTTGAAACTTCGTCGTCTGCCACTAGCTTCACGCTCCATCAACTTGCGTTCCATCCTGAGATCCAAGAGAAAGTGCAAAAAGAACTAGATCAGGTTCTCGCCAAATATAACAACAAGCTGTGCTACGATGCGATCAAAGAGATGAGATACTTGGAGAGTGCGTTTAAAGAGGCCATGAGAATGTTTCCGTCGCTCGGTTTCTTGATTAGGGAGTGCGCTCGTCAATACACATTCCCGGAGTTAAACTTGACTATAGACGAAGGCGTAGGTATAATCATACCTCTCCAGGCCTTGCACAATGACCCTGAATATTTTGATAGTCCGAATGAATTCCGACCAGAAAGATTCATGCCCTCTGAATATAATCATAACAAAACGAAATTTGTCTACTTACCTTTTGGCGATGGACCACGTGGTTGCATCGGTGCTCGCCTTGGCTTAATGCAGTCCTTGGCAGGCTTGGCAGCCGTCCTGTCCAAGTTCACGGTGAAGCCAGCTCCGAACACAAAGCGTCATCCGGTCGTTGAACCCAAATCCAGCATCGTGCAGAGCTTCAAAGATGACCTGCCTCTGCTCTTCATTGAGAGGACAAAGCCCTGA
Protein sequence (511 aa)
MLTAAIFVIIVALVYLYSTRTFRYWEKRGIKHDKPVPFFGTDSEGYLLRKSMTQTAVDAYLKYPNEKVIGFFRSSRPELIIRDPDIIKRILTTDFAYFYPRGLNPHKKVIEPLMRNLFFADGDLWRLLRQRMTPAFTSGKLRAMFPLVVERAERLQSRTLEIASQPLDARELMARYTTDFIGACGFGLDADSLNDEDSAFRKLGAAIFNITVQQAIVAALKEIFPGIFKHFKYSSKYETDFMSLVSSILKQRNYKPSGRNDFIDLLLECRMKGEIVVESIEKMKPDGTSEVVRMELTEQLLAAQVFIFFAAGFETSSSATSFTLHQLAFHPEIQEKVQKELDQVLAKYNNKLCYDAIKEMRYLESAFKEAMRMFPSLGFLIRECARQYTFPELNLTIDEGVGIIIPLQALHNDPEYFDSPNEFRPERFMPSEYNHNKTKFVYLPFGDGPRGCIGARLGLMQSLAGLAAVLSKFTVKPAPNTKRHPVVEPKSSIVQSFKDDLPLLFIERTKP
Domains and motifs
| Database | ID | Description | Start | End | Evalue | InterPro ID |
|---|---|---|---|---|---|---|
| PANTHER | PTHR24292 | - | 3 | 493 | 1.7e-128 | - |
| PANTHER | PTHR24292:SF93 | - | 3 | 493 | 1.7e-128 | - |
| Gene3D | 1.10.630.10 | - | 13 | 506 | 1.2e-115 | IPR036396 |
| SUPERFAMILY | SSF48264 | - | 34 | 508 | 1.2e-100 | IPR036396 |
| Pfam | PF00067 | Cytochrome P450 | 36 | 494 | 1.8e-89 | IPR001128 |
| ProSitePatterns | PS00086 | Cytochrome P450 cysteine heme-iron ligand signature. | 445 | 454 | - | IPR017972 |
InterPro assignment
| InterPro ID | InterPro description |
|---|---|
| IPR001128 | Cytochrome P450 |
| IPR017972 | Cytochrome P450, conserved site |
| IPR036396 | Cytochrome P450 superfamily |
Gene ontology (GO) assignment
| GO category | GO ID | GO description |
|---|---|---|
| molecular function | GO:0005506 | iron ion binding |
| molecular function | GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| molecular function | GO:0020037 | heme binding |
| biological process | GO:0055114 | oxidation-reduction process |
| Species | Accession |
|---|---|
| Danaus plexippus | DPOGS211695 |
| Heliconius melpomene | HMEL003453-RA HMEL003682-RA |
| Manduca sexta | XP_030030148.1 |
| Plutella xylostella | g25354.t1 |
| Spodoptera frugiperda (corn) | GSSPFG00012279001.2-PA |
| Spodoptera frugiperda (rice) | SFRICE012783.2-PA SFRICE025586.2-PA |
| Acyrthosiphon pisum | XP_001944599.2 XP_016657118.1 XP_029344865.1 |
| Aedes aegypti | AAEL008889-PA |
| Anopheles gambiae | AGAP002868-PA |
| Apis mellifera | NP_001035324.1 XP_026300343.1 XP_026300535.1 XP_395671.3 |
| Drosophila melanogaster | FBpp0084553 FBpp0086585 FBpp0308423 |
| Tribolium castaneum | XP_015835338.1 XP_969633.1 |
| Homo sapiens | - |
| Mus musculus | - |