Position
| Chromosome | chr22 |
| Start | 13801731 |
| End | 13808376 |
| Strand | - |
view in Gbrowse: chr22:13801731..13808376
Most similar sequence in NCBI nr database
| Accession | Description | E-value | Score |
|---|---|---|---|
| XP_004927162.1 | esterase E4 isoform X1 | 0.0 | 1221 |
ORF sequence (1773 bp)
ATGTTCTTATTTAAAAGAACACACAAATTGCTGCTTCGAACGAAACACTTCAAGGAGTTTTTTACCTCAACAAAAATAATAAATAATATGAGATGTGGAGTTAGACAGCATATTAAAATCATCTCATTCGCTGTGTCCAACCTCGTAAACCCTGCCAAGGATAATCCACTGGTGACAGTTGAACAAGGAACTCTAAGAGGCTCTAAGAAAACCCTACTCGATGGATCCCCATACTACAGTTTTAAGGGAATTCCTTATGCAGAACCACCTATTGGAGAGCTCAGATTTCAGGCGCCAAAACCTCGTAAGCCGTGGAATGGGGTCCTTGATGCTGTCGAGCACGGACCCGTGTGTCCTCAATATGACATTAGTACTTCTTCAACGATTGAAGGAAACGAAGATTGTTTGTATTTAAACGTTTATACCAGATCTTTACAGTCGGATAGTAAAATACCAGTCATGGTATACATTCACGGCGGAGGCTACTCGTCTGGTTCGGGCAATTCGGGAATGTACGGCCCGGAGTTCATTATTCAGCACAACGTTGTTCTGGTCACGATAAACTATAGACTCGAACTTTTGGGTTTTCTTAGTTTAGACACGGCCGAAGTTCCAGGCAACGCCGGGATGAAGGATCAGGTTGCCGCGTTGCGATGGGTCAAAGGTAACATCGTAAGGTTTGGCGGTGATCCTGATAATGTAACAATTTTCGGGGAAAGTGCGGGGGCCGCGTCCGTCACGTATCACATGCTTTCACCAATGTCGAAAGGTCTGTTCCATAAGGTAATCGCTCAAAGCGGTGTTTGTATTAACGACTGGGCGATAGGCAACAAAACCTTGGAAAGAGTATACAGAGTTGCGAATTTATTAGGTAAAGAGTGTAGTGATGTACAAGATTTGTTGGAGTTTTTGAGGAGCGTTGATCCTCTCAAGCTAACCTGCGTGACTTACAGAACAAGGACGCAAGATGAAAAGTACAGAGGACTGCCAATGTACTTTGTTCCGATTGTAGAGAAGAAATTCGATGGTGTCGAAGCATTTTTGAGCGAGGAACCAATCGAGACGCTTATGTCTGGTAATATTAACAACGTACCGATACTGTTGGGCTACAATAAATCTGAAGGAGTGTTGATGGTGGCGGATGTATTAAAAAAAAAAGAAATTATGAACGAAAAGCCTTCGTTTATTGTACCTAGGGAAATAGCGCAAACCGTTTCCGAAGAGAAAATAAAGGAATTTGGTGAGAGGATCAAGAGATTTTACTTTGGTGACGAGGGAATATCAGCGGACAACACAGCAACAATTGTCGATTTTCAAACAGATCTCTATTTTGCATACAACGTCCATAGATTTGCATATTTATACAGCGTTTACAATTATCCAATTTATTTATACAGATTCGATTATGAAACTGAATTGAATTTCATTAAAAACGCGTTAGGCCAGGGCGGAATAAAAGGTGCAGCCCACGCCGACGACCTGTTCTATTTCTTTTACAATCCCATAAACAAACATTTGATTGGAGATGAGCGATTGAAGATAATAATTTACGAAGTAACGAAACTTTGGACTGATTTTAGTAAAACGGGAAATCCAACACCGGACAACGCTTTGGGTGTCAAATGGTATCCGTACAGCGTGAACGGGAACAAAATTATGTTTTTGGATGAGCCTTTGAGATTCGAACAATGCTTTGAAATTGATAGGGTCGATTTTTGGAACAAACTGTACTCGGAAGCAGGCAGGCCGTGTATTAAAAAAAGCAATTTATGA
Protein sequence (590 aa)
MFLFKRTHKLLLRTKHFKEFFTSTKIINNMRCGVRQHIKIISFAVSNLVNPAKDNPLVTVEQGTLRGSKKTLLDGSPYYSFKGIPYAEPPIGELRFQAPKPRKPWNGVLDAVEHGPVCPQYDISTSSTIEGNEDCLYLNVYTRSLQSDSKIPVMVYIHGGGYSSGSGNSGMYGPEFIIQHNVVLVTINYRLELLGFLSLDTAEVPGNAGMKDQVAALRWVKGNIVRFGGDPDNVTIFGESAGAASVTYHMLSPMSKGLFHKVIAQSGVCINDWAIGNKTLERVYRVANLLGKECSDVQDLLEFLRSVDPLKLTCVTYRTRTQDEKYRGLPMYFVPIVEKKFDGVEAFLSEEPIETLMSGNINNVPILLGYNKSEGVLMVADVLKKKEIMNEKPSFIVPREIAQTVSEEKIKEFGERIKRFYFGDEGISADNTATIVDFQTDLYFAYNVHRFAYLYSVYNYPIYLYRFDYETELNFIKNALGQGGIKGAAHADDLFYFFYNPINKHLIGDERLKIIIYEVTKLWTDFSKTGNPTPDNALGVKWYPYSVNGNKIMFLDEPLRFEQCFEIDRVDFWNKLYSEAGRPCIKKSNL
Domains and motifs
| Database | ID | Description | Start | End | Evalue | InterPro ID |
|---|---|---|---|---|---|---|
| Gene3D | 3.40.50.1820 | - | 18 | 582 | 0.0 | IPR029058 |
| PANTHER | PTHR43142 | - | 38 | 580 | 0.0 | - |
| PANTHER | PTHR43142:SF1 | - | 38 | 580 | 0.0 | - |
| SUPERFAMILY | SSF53474 | - | 54 | 577 | 0.0 | IPR029058 |
| Pfam | PF00135 | Carboxylesterase family | 55 | 573 | 0.0 | IPR002018 |
| ProSitePatterns | PS00941 | Carboxylesterases type-B signature 2. | 133 | 143 | - | IPR019819 |
| ProSitePatterns | PS01173 | Lipolytic enzymes "G-D-X-G" family, putative histidine active site. | 154 | 170 | - | IPR002168 |
| ProSitePatterns | PS00122 | Carboxylesterases type-B serine active site. | 227 | 242 | - | IPR019826 |
InterPro assignment
| InterPro ID | InterPro description |
|---|---|
| IPR002018 | Carboxylesterase, type B |
| IPR002168 | Lipase, GDXG, putative histidine active site |
| IPR019819 | Carboxylesterase type B, conserved site |
| IPR019826 | Carboxylesterase type B, active site |
| IPR029058 | Alpha/Beta hydrolase fold |
Gene ontology (GO) assignment
| GO category | GO ID | GO description |
|---|---|---|
| molecular function | GO:0016787 | hydrolase activity |
| Species | Accession |
|---|---|
| Danaus plexippus | DPOGS211394 |
| Heliconius melpomene | HMEL017092g1.t1 HMEL017092g1.t2 |
| Manduca sexta | XP_030039765.1 |
| Plutella xylostella | g25414.t1 |
| Spodoptera frugiperda (corn) | GSSPFG00000131001.3-PA GSSPFG00020288001.5-PA |
| Spodoptera frugiperda (rice) | - |
| Acyrthosiphon pisum | XP_029344195.1 |
| Aedes aegypti | AAEL019679-PA AAEL019679-PB AAEL019679-PC AAEL019679-PD AAEL019679-PE |
| Anopheles gambiae | AGAP006727-PA |
| Apis mellifera | XP_026299635.1 XP_392696.5 |
| Drosophila melanogaster | - |
| Tribolium castaneum | NP_001034534.1 XP_008195481.1 |
| Homo sapiens | NP_001177130.1 NP_001305435.1 NP_001351711.1 NP_776176.5 XP_011521323.1 XP_011521325.1 XP_011521326.1 XP_011521327.1 XP_011521328.1 XP_011521329.1 XP_011521330.1 XP_011521332.1 XP_016878649.1 XP_016878650.1 XP_016878652.1 XP_016878653.1 XP_016878654.1 XP_024306002.1 |
| Mus musculus | NP_666325.2 |