Position
| Chromosome | chr23 |
| Start | 17062232 |
| End | 17114469 |
| Strand | - |
view in Gbrowse: chr23:17062232..17114469
Most similar sequence in NCBI nr database
| Accession | Description | E-value | Score |
|---|---|---|---|
| XP_028034924.1 | multidrug resistance protein homolog 49-like | 0.0 | 2694 |
ORF sequence (3948 bp)
ATGAAGGGACAAAGCAAACGTTTCGTTAGCCATAAAGGCAAGGCTTACGATATAGGCGTTAAGAAGAAACAGGATGTGGGAATCGGGTTCTTGGATCTGTGGCGCTACGCGACAACAACCGAGAGACTGGTCACGTTCCTTGGGGTGCTTCTGTCTTTTTGCTGCTCGTGTGGCCTAGTGGCGGCCGTCGTCATCTATGGCGAGCTGACATCGCTGTTCGTTCAGAGGAACAATGCTGCTCCTACCACTCCTCACGGTCACATCCTCGGTTTGTTCGGCGGAGGAAGAGTATTGCCTGGCGGAAATCGTTCCCTTCATATGGACGCTTTAGTGGAAGACTCCAGGGCGTTTGGATTGGCTAGCGTGGTGATCATGATAATGCAGATGACGACTGCCGCGTTTGCCGTCATCACGGCGAACTGGGCCGCTACTAGAATGGTAACAAGATTACGTCTTCGGATCCTGCGATCGGTATTAAGTCAAGAGATAGCATTTTTCGATACAAACACTACAATGAATTTCGCGTCGACGTTGACAGAGGACATGGAGAAGCTACAAGCGGGAGTGGGGGAGCATGTCGTGATGACGACATACTTAGCCGGGACGGTTGTGTGTGGCTCAGCTCTATCTCTTTCATACGGCTGGGAGCTGACATTAGCCGGGCTCTCTGTGGTTCCTGTTGCTATCCTTGTCGCAACAGTTGTTGCTAAGTACCAAACTAAATGTTCGACCAATGAGGTGGTGGCGTACGGAGTTGCCGGAAGAATAGTCGAGGAGGTATTGTCTGCTATTAGGACAGTAAGGGCTTATGGTGGAGAGGAACTTGAAGTTAAAAGGTACTCGGAAGCTCTAAAGCCAGCGGCCTCACACGCTCGTCGTCGTGGTCTCTGGGCTGGGGCGGGTTCAGGTCTTGGCTGGCTGCTCACCTACAGTCTAAACGCTATAGTCCTGGCTTACGGAACAGCTTTATGCGTCAGAGACTCGGATCTACCCCCAGAAGAACAGGATTACCATCCTGGCATCATGGTTACTATTCTGTTCTGCACTTTCGTGGCGGCGCAGAATATAGCGATGTGCAACCCTCATCTGGAGATATTCTCGACGGCGCGTGGAGCTGCCAAATCTCTATTCAAGCTAATCGAGAGGAAGTCCAATATCGACGCACTGGAGAACGTAGGAGTTAAGCCGGAGAGCTTCAGAGGCGATATCCAGTTCGAGAATCTGTACTTCAATTACCCTTCGAGACCCGACGTGAAGGTCCTAAGGGGGCTGACCCTCAAGATATCAGCGGGGGAGACAGTGGCCCTAGTCGGTTCCTCGGGCTGCGGTAAGTCGACGCTGCTGCAACTCCTGCAGAGGATGTACGAGCCCGAAACTGGACGAGTAGTTGTTGATGGCCATCCCCTAAACAAACTTCATCTGCACCATTTCAGGAAGAGCATAGGCGTGGTCGGCCAAGAACCAGTGCTCTTCTGCGGAACGATCAGAGAGAACATCACTTTCGGGATGGACGACGTCACAGAGGAACAGATGATCGAGGCAGCCAAAACTGCGCACGCGCATCAATTCATCACCAAACTCGCAAATGGCTATGACACCATGCTGGGAGAGCGCGGCGCTGCCCTATCTGGTGGACAGAAGCAGAGAATCGCGATAGCACGTGCCATAGTCAGACGTCCCGCTGTCTTGCTATTGGACGAGCCGACTTCTGCGCTAGACCCTGCTGCTGAGAAACAGGTCCAAGCAGCCCTGGACGCAGCTAGTAAAGGGCGCACCACACTCGTAGTCTCGCACAGACTATCGACCATTGCAAATGCTTCAAAGATCGTCTACATCGAACAAGGATCCGTGTTGGAGCAGGGAACTCATGCGGAACTGCTAGAGAAAAAAGGAAATTACTGGAAATTGCTCAACGAAGATCTGACTAGCAAGAGCATAGCAGCCACGTTATCAGCGGCCGGAAACGATGATGACGACGAGGTACTAGAGACTGTTGAAGAATGTCGTTTCCGAAGGTCCGTCAGCAGACAATCGATGCATCGAGAATCTATGAATCGGAACCACTTCGTGCGGGGCAGTCGCCGATTGAGGTCCATCTCATCGGCCCATCTGCCGGTCACCGCTGTGCCCGATCTCCTCAACTACGTGGAACCGGAAGAGACGGAAGACGAATCAGTCCCAGAGGTGTCCAGCTTGGCGCTGATGAAGCTGAACGCTCCGGAGTGGCCGCTGCTGATGGGCGGTGGCGTCGCCTCATTCTTGGTCGGTTCAACGATGCCGATATTCGCTTTGCTCTTCTCCAAATTATACGGGATGTTCGCCTCTGATGACACGGACGCGATCCTCGAGCAGTCGCAGCTGTATGCGGGACTCTTCGCCGGAGTCGCGGCCGCCTGCGGGATCGTCAACTTCCTCCAGACGTGGCTCCTGAGCAAGGCCGGCTCCAAGCTCACCGACAGACTGAGAGAGCACAGTTTCAGGAACTATTTGAAACAGGAGCAAGGCTGGTTTGACGAGCAAGCTAATTCTGTCGGGGCTCTCTGCGCCAGACTCTCCTCTGACTGCGCTGCTGTACAAGGAGCTACAGGTACCAAATTGGGGACGGTGCTCCAAGGCGTGAGCACGATGGTTATCGGTGTCGGACTGGCAATGGCATACTCGTGGAAGATGACATTAGTTAGCCTGACAAGCGTTCCTTGTGTCATGGGCGCCATCTATCTCGAAGGCTACGTGAACAAACGCACCGAAGAGAAACAGAAGAAAGCGATAGAGCACGCTTCGCGCGTCGCCACTGAAGCAGTACTGAACGTGCGCACCGTACAGAGCCTGGGTGTGGAGCTGACAGTCTTGGAGAAGTACGAACGCGCGCTGATGGGGGGTGGCGGTAGAGGGGGGAGTGGCGCAATGCGAGGCGCGGTGTACGGGGCGTGTCTGTGCGCACCTACGCTCGGTTACGCCGTGTCGTTAGCCTACGGAGGCTATCTCATCGCAACCGAAGGCCTGCACTATGAATACGCTATTCTGGTGTCCGAGGCGCTGATCTACGGAGCGTGGATGCTGGCTGAAGCGCTCTCATTCGCGCCAAACTTCGCCGCCGCCAAGCGCTCTGGGGCCAGGATCATTAATGCCCTAGCCAGGGAACCGAAGATCGTAACTGAACCAACAGCGAAGGATGAACCAGCATGGACCGCGAAAGGAGAGGTTAACTTCTCTGATTTACACTTCAACTATCCAACTCGGCCTTCAGTGCCGGTCCTGCGAGGCCTGAACCTTCAGCTCAAGGCCGGGCGCACTGTAGCGCTCGTCGGGGCCAGCGGCTGCGGGAAATCCACTCTGATGCACCTTATCATGAGGAGCTATGACCCTACTAAAGGCAAAGTTGAACTAGACGGGAGAGATATAAAGCGCGATCTTTCGCTGCCCAGTCTGAGATCGAACCTGGGACTCGTGCAACAAGAACCAGCGCTTTTCGAACGTTCAATCAGGGAAAATATTGCATACGGAGACAATTCACGGGATGTGACCTTGGAAGAGATTATAGACGCTGCGAAACAAGCGAACGTACACGGTTTTGTGGCGGGCTTACCTTTGGGCTACGAAACGAAGCTGGGACAAGGCGGAGCTGCTCTGTCCGGGGGACAGAAGCAGAGGATCGCGATCGCAAGGGCCTTGGTACGAAACCCGAGGGTTTTGCTACTGGACGAAGCCACATCAGCCTTGGATGCTTCCAGTGAAAAGGTGGTGCAAAGCGCTCTGGAAGTCGCCGCCAAAGATCGAACGACAATTATAATAGCTCATCGACTAGCTACGATCAGACATGCACACACGATATGCGTGGTCGAGAACGGAGTCATAGCCGAAAGCGGATCACATGACGAGCTGGTCCGAAAACGTGGACTTTACTGGGAATTATTGCAGCAGCAAGGACCCTCGGAAGCGAAAGCGTGA
Protein sequence (1315 aa)
MKGQSKRFVSHKGKAYDIGVKKKQDVGIGFLDLWRYATTTERLVTFLGVLLSFCCSCGLVAAVVIYGELTSLFVQRNNAAPTTPHGHILGLFGGGRVLPGGNRSLHMDALVEDSRAFGLASVVIMIMQMTTAAFAVITANWAATRMVTRLRLRILRSVLSQEIAFFDTNTTMNFASTLTEDMEKLQAGVGEHVVMTTYLAGTVVCGSALSLSYGWELTLAGLSVVPVAILVATVVAKYQTKCSTNEVVAYGVAGRIVEEVLSAIRTVRAYGGEELEVKRYSEALKPAASHARRRGLWAGAGSGLGWLLTYSLNAIVLAYGTALCVRDSDLPPEEQDYHPGIMVTILFCTFVAAQNIAMCNPHLEIFSTARGAAKSLFKLIERKSNIDALENVGVKPESFRGDIQFENLYFNYPSRPDVKVLRGLTLKISAGETVALVGSSGCGKSTLLQLLQRMYEPETGRVVVDGHPLNKLHLHHFRKSIGVVGQEPVLFCGTIRENITFGMDDVTEEQMIEAAKTAHAHQFITKLANGYDTMLGERGAALSGGQKQRIAIARAIVRRPAVLLLDEPTSALDPAAEKQVQAALDAASKGRTTLVVSHRLSTIANASKIVYIEQGSVLEQGTHAELLEKKGNYWKLLNEDLTSKSIAATLSAAGNDDDDEVLETVEECRFRRSVSRQSMHRESMNRNHFVRGSRRLRSISSAHLPVTAVPDLLNYVEPEETEDESVPEVSSLALMKLNAPEWPLLMGGGVASFLVGSTMPIFALLFSKLYGMFASDDTDAILEQSQLYAGLFAGVAAACGIVNFLQTWLLSKAGSKLTDRLREHSFRNYLKQEQGWFDEQANSVGALCARLSSDCAAVQGATGTKLGTVLQGVSTMVIGVGLAMAYSWKMTLVSLTSVPCVMGAIYLEGYVNKRTEEKQKKAIEHASRVATEAVLNVRTVQSLGVELTVLEKYERALMGGGGRGGSGAMRGAVYGACLCAPTLGYAVSLAYGGYLIATEGLHYEYAILVSEALIYGAWMLAEALSFAPNFAAAKRSGARIINALAREPKIVTEPTAKDEPAWTAKGEVNFSDLHFNYPTRPSVPVLRGLNLQLKAGRTVALVGASGCGKSTLMHLIMRSYDPTKGKVELDGRDIKRDLSLPSLRSNLGLVQQEPALFERSIRENIAYGDNSRDVTLEEIIDAAKQANVHGFVAGLPLGYETKLGQGGAALSGGQKQRIAIARALVRNPRVLLLDEATSALDASSEKVVQSALEVAAKDRTTIIIAHRLATIRHAHTICVVENGVIAESGSHDELVRKRGLYWELLQQQGPSEAKA
Domains and motifs
| Database | ID | Description | Start | End | Evalue | InterPro ID |
|---|---|---|---|---|---|---|
| PANTHER | PTHR24221 | - | 26 | 1308 | 0.0 | IPR039421 |
| PANTHER | PTHR24221:SF410 | - | 26 | 1308 | 0.0 | - |
| SUPERFAMILY | SSF90123 | - | 33 | 382 | 2.2e-44 | IPR036640 |
| Gene3D | 1.20.1560.10 | - | 34 | 664 | 5.6e-200 | IPR036640 |
| CDD | cd18577 | ABC_6TM_Pgp_ABCB1_D1_like | 46 | 376 | 2.5e-73 | - |
| Pfam | PF00664 | ABC transporter transmembrane region | 46 | 326 | 8.0e-51 | IPR011527 |
| ProSiteProfiles | PS50929 | ABC transporter integral membrane type-1 fused domain profile. | 46 | 368 | 36.174 | IPR011527 |
| Gene3D | 3.40.50.300 | - | 396 | 642 | 5.6e-200 | - |
| SUPERFAMILY | SSF52540 | - | 396 | 638 | 1.5e-86 | IPR027417 |
| CDD | cd03249 | ABC_MTABC3_MDL1_MDL2 | 403 | 636 | 3.0e-125 | - |
| ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. | 403 | 639 | 28.018 | IPR003439 |
| Pfam | PF00005 | ABC transporter | 421 | 570 | 8.4e-37 | IPR003439 |
| SMART | SM00382 | - | 430 | 616 | 6.0e-18 | IPR003593 |
| ProSitePatterns | PS00211 | ABC transporters family signature. | 542 | 556 | - | IPR017871 |
| Gene3D | 1.20.1560.10 | - | 728 | 1033 | 1.2e-70 | IPR036640 |
| SUPERFAMILY | SSF90123 | - | 734 | 1053 | 2.1e-46 | IPR036640 |
| CDD | cd18578 | ABC_6TM_Pgp_ABCB1_D2_like | 735 | 1050 | 1.3e-109 | - |
| ProSiteProfiles | PS50929 | ABC transporter integral membrane type-1 fused domain profile. | 747 | 1032 | 36.484 | IPR011527 |
| Pfam | PF00664 | ABC transporter transmembrane region | 748 | 1012 | 4.7e-49 | IPR011527 |
| Gene3D | 1.20.1560.10 | - | 1034 | 1059 | 5.4e-125 | IPR036640 |
| Gene3D | 3.40.50.300 | - | 1060 | 1309 | 5.4e-125 | - |
| SUPERFAMILY | SSF52540 | - | 1060 | 1308 | 2.8e-83 | IPR027417 |
| CDD | cd03249 | ABC_MTABC3_MDL1_MDL2 | 1068 | 1308 | 2.0e-128 | - |
| ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. | 1068 | 1307 | 25.464 | IPR003439 |
| Pfam | PF00005 | ABC transporter | 1086 | 1238 | 3.0e-36 | IPR003439 |
| SMART | SM00382 | - | 1095 | 1284 | 3.1e-20 | IPR003593 |
| ProSitePatterns | PS00211 | ABC transporters family signature. | 1210 | 1224 | - | IPR017871 |
InterPro assignment
| InterPro ID | InterPro description |
|---|---|
| IPR003439 | ABC transporter-like |
| IPR003593 | AAA+ ATPase domain |
| IPR011527 | ABC transporter type 1, transmembrane domain |
| IPR017871 | ABC transporter, conserved site |
| IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| IPR036640 | ABC transporter type 1, transmembrane domain superfamily |
| IPR039421 | Type I protein exporter |
Gene ontology (GO) assignment
| GO category | GO ID | GO description |
|---|---|---|
| molecular function | GO:0005524 | ATP binding |
| cellular component | GO:0016021 | integral component of membrane |
| molecular function | GO:0016887 | ATPase activity |
| molecular function | GO:0042626 | ATPase-coupled transmembrane transporter activity |
| biological process | GO:0055085 | transmembrane transport |
| Species | Accession |
|---|---|
| Danaus plexippus | DPOGS214416 DPOGS214432 |
| Heliconius melpomene | HMEL008785g1.t1 |
| Manduca sexta | XP_030029781.1 |
| Plutella xylostella | g4175.t1 |
| Spodoptera frugiperda (corn) | GSSPFG00015024001.2-PA |
| Spodoptera frugiperda (rice) | SFRICE013838-PA |
| Acyrthosiphon pisum | XP_001947434.2 XP_016656026.1 |
| Aedes aegypti | AAEL010379-PA AAEL010379-PB AAEL010379-PC |
| Anopheles gambiae | AGAP005639-PA AGAP005639-PB |
| Apis mellifera | XP_006569045.1 XP_006569046.1 XP_016773577.1 |
| Drosophila melanogaster | FBpp0086914 |
| Tribolium castaneum | XP_008191266.1 XP_015833809.1 |
| Homo sapiens | NP_000918.2 NP_001335873.1 NP_001335875.1 |
| Mus musculus | XP_006503616.1 |