Position
| Chromosome | chr22 |
| Start | 460496 |
| End | 476418 |
| Strand | + |
view in Gbrowse: chr22:460496..476418
Most similar sequence in NCBI nr database
| Accession | Description | E-value | Score |
|---|
| XP_004925915.2 | ATP-binding cassette sub-family B member 7, mitochondrial isoform X3 | 0.0 | 1444 |
ORF sequence (2109 bp)
ATGGCGGTCGCACTATTAATAAATAAAAGAATTCAAAAAGTATTCCGAACACATGTTAAATTAGTTAGATCTGTTACTAGTAACCATTCTATAATATTAAATAAACCGCAATTAAGCATAGTATGTAAGCAATGTGCTGTTACGAGCTATCTCAGATTTTATTCGTCGCCAAGCCCGAACAATCAGGGGGGTCAGGATTCCGCCAAAAATGTTTTGGCGGCAGTGTTGGCAAACAAACCAAAGACTGGGAAAATACCCGTTGATATAAGCCTGGGTGATACGAAACCTGTTTCCACTGTGGACATGTTCAGGGGCTTGATGGAGTATGTATGGCCTAAGGATAACCAAGCCATCCGGAATCGTGTAACACTGTCCCTGTCACTCCTGTTTGGTGCGAAAGTGATGAATGTGACGGTGCCATTCCTTTTTAAATATGCTGTGGACGAAGTGAACCAAGTGGCGACGACACCGGCCGGAGACGCGCTGCTCGGCATGGCCACTGTGCCGCAGGCGTTAGGAACAACAGCTTTCAGCTTATTGGTAGGATACGGGCTGGCGCGCGCCACGGCGGCCGGCTTCAACGAGCTGCGCAACGCCGTGTTCGCGCGCGTCGCCCAGCACTCCATCCGCCGCCTCGCCTGCAACGTCTTCACGCATCTGCACAACCTGGACCTCGGCTTCCATCTCGGCAGGCAGACCGGGGCCCTGTCCAAGACAATAGACAGGGGGTCGAGGGCCATAAACTTTGTCCTTTCGGCCATGATTTTCAACGTTGTACCGACCATATTCGAGCTCACATTGGTGTCTACTATACTGGGAGTCAAGGGAGGACTTGCTTTTGCGGGGCTGGCGGTCGGCTGCGTGGGAGTGTACGCCGCCTTCACGCTCGCCATCACGCAGTGGAGGACGCAGTTCCGCGTGCGCATGAACCGCGCGGAGAACCAGGCCGGCAACACCGCCATCGACTCGCTCATCAACTACGAGACCGTCAAGTACTTCAACAACGAGCGCCACGAGCTCGAGAAGTACGACGCCAGCCTGCGCCAGTACGAGAGCGCGTCCCTCAAGACGGCGTGGAGCCTCGCCGCGCTCAACTTCGGACAACACGCCATCTTCAGCGCCGGACTCAGCCTCGTCATGCTGCTCGCCGCCCGGGAGATAGCCGCCGGTAGCATGACGGTGGGCGACTTGGTGATGGTGAACGGTCTCCTGTTCCAGCTGTCCATCCCGCTCGGCTTCCTGGGCTCCGTGTACCGGGAGGTGCGCCAGGCGCTCGTCGACATGCAGACCATGTTCACGCTCATGACCGTGCAGTCCCGGATCAAGGAGATACAGAAAGCTCCGCCGCTGATCGTGGACAGTAGGACGGCCACGATAGAGTTCAGAGACGTGAACTTCAAGTACGTGAACGGGAAGCCGATATTCAACAACCTCAGCTTCTCGATCCCGGCCGGCGCCAAGATCGGCATCGTGGGCGGCTCGGGCTCCGGAAAATCCACAATGGTCCGACTGTTGTACCGATTCTTCGAACCGCAGTCCGGGAACATATTCATCAACGGACAGAACATCCGGGACGTGGACCTGGTTAGCTTGAGGAAGGCCATCGCAGTCGTTCCGCAGGACTGCGTGCTGTTCCACGACACGATATTCCACAACCTGCACTACGGAGACCTGAGCAAGTCCCGGGAGCAGGTGTACGCCGCCAGCAGACTCGCCGAGCTGCACGACGCGGTGCTCACCTGGCCCAAGGGCTATGAGACGGAGGTCGGCGAGCGCGGCCTGAAGCTGTCCGGGGGCGAGAAGCAGCGCGTGGGCATCGCGCGCGCCATCCTCAAGGACGCGCCGCTGCTGCTGCACGACGAGGCCACCTCCAGCCTCGACTCCCTCACCGAGCACGCGATCCTGCAAGCGTTGAAGGCAGCGACGGTCGGGAAGACGTCGATCTGCATCGCGCACCGCCTCTCCACCGTGGCCGACGCCGACGAGATCCTCGTGCTGGAGCGCGGCGCCATCAGCGAGCGCGGCTCCCACCACCAGCTCGTCGCCAACCCCTCGTCCCTGTACTACAAGCTCTGGGAGAAACAGAACCAACATCCCTTATCCAAGTGA
Protein sequence (702 aa)
MAVALLINKRIQKVFRTHVKLVRSVTSNHSIILNKPQLSIVCKQCAVTSYLRFYSSPSPNNQGGQDSAKNVLAAVLANKPKTGKIPVDISLGDTKPVSTVDMFRGLMEYVWPKDNQAIRNRVTLSLSLLFGAKVMNVTVPFLFKYAVDEVNQVATTPAGDALLGMATVPQALGTTAFSLLVGYGLARATAAGFNELRNAVFARVAQHSIRRLACNVFTHLHNLDLGFHLGRQTGALSKTIDRGSRAINFVLSAMIFNVVPTIFELTLVSTILGVKGGLAFAGLAVGCVGVYAAFTLAITQWRTQFRVRMNRAENQAGNTAIDSLINYETVKYFNNERHELEKYDASLRQYESASLKTAWSLAALNFGQHAIFSAGLSLVMLLAAREIAAGSMTVGDLVMVNGLLFQLSIPLGFLGSVYREVRQALVDMQTMFTLMTVQSRIKEIQKAPPLIVDSRTATIEFRDVNFKYVNGKPIFNNLSFSIPAGAKIGIVGGSGSGKSTMVRLLYRFFEPQSGNIFINGQNIRDVDLVSLRKAIAVVPQDCVLFHDTIFHNLHYGDLSKSREQVYAASRLAELHDAVLTWPKGYETEVGERGLKLSGGEKQRVGIARAILKDAPLLLHDEATSSLDSLTEHAILQALKAATVGKTSICIAHRLSTVADADEILVLERGAISERGSHHQLVANPSSLYYKLWEKQNQHPLSK
Domains and motifs
| Database | ID | Description | Start | End | Evalue | InterPro ID |
|---|
| PANTHER | PTHR24221 | - |
88 | 697 | 0.0 |
IPR039421 |
| PANTHER | PTHR24221:SF187 | - |
88 | 697 | 0.0 |
- |
| SUPERFAMILY | SSF90123 | - |
106 | 435 | 1.6e-51 |
IPR036640 |
| Gene3D | 1.20.1560.10 | - |
109 | 447 | 1.1e-126 |
IPR036640 |
| Pfam | PF00664 | ABC transporter transmembrane region |
123 | 409 | 2.6e-30 |
IPR011527 |
| ProSiteProfiles | PS50929 | ABC transporter integral membrane type-1 fused domain profile. |
124 | 423 | 38.99 |
IPR011527 |
| CDD | cd18582 | ABC_6TM_ATM1_ABCB7 |
125 | 431 | 8.6e-157 |
- |
| Gene3D | 3.40.50.300 | - |
450 | 701 | 1.1e-84 |
- |
| SUPERFAMILY | SSF52540 | - |
452 | 695 | 7.2e-82 |
IPR027417 |
| ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. |
459 | 693 | 23.063 |
IPR003439 |
| Pfam | PF00005 | ABC transporter |
476 | 624 | 1.2e-31 |
IPR003439 |
| SMART | SM00382 | - |
484 | 670 | 2.5e-13 |
IPR003593 |
| ProSitePatterns | PS00211 | ABC transporters family signature. |
596 | 610 | - |
IPR017871 |
InterPro assignment
| InterPro ID | InterPro description |
|---|
| IPR003439 | ABC transporter-like |
| IPR003593 | AAA+ ATPase domain |
| IPR011527 | ABC transporter type 1, transmembrane domain |
| IPR017871 | ABC transporter, conserved site |
| IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| IPR036640 | ABC transporter type 1, transmembrane domain superfamily |
| IPR039421 | Type I protein exporter |
Gene ontology (GO) assignment
| GO category | GO ID | GO description |
|---|
| molecular function | GO:0005524 | ATP binding |
| cellular component | GO:0016021 | integral component of membrane |
| molecular function | GO:0016887 | ATPase activity |
| molecular function | GO:0042626 | ATPase-coupled transmembrane transporter activity |
| biological process | GO:0055085 | transmembrane transport |