Position
| Chromosome | chr19 |
| Start | 12760835 |
| End | 12809590 |
| Strand | + |
view in Gbrowse: chr19:12760835..12809590
Most similar sequence in NCBI nr database
| Accession | Description | E-value | Score |
|---|---|---|---|
| XP_021202385.1 | ATP-binding cassette sub-family A member 3 | 0.0 | 2443 |
ORF sequence (4554 bp)
ATGGATTGCCATTCCGTTAAGGTATTAATGTGGAAACACCTCACGGTGCGTATGAGGAGGTACTTTCACACCCTTGTAGAGCTTCTGTCGCCAATAGCATTGATTTTGCTATTCAGTGCTCTAAATATTGTTAAGACACCTCCCGATCATGTTGTGTCATCAGCTCAATACAACCCAGAATATCATTCTAAGAACTTTGAACGTCCAAACTGCATTTATTATTATCCAGAAACGAACCTTACAAAAACACTCATGGACCAAGTTGCCAAGAAATTCCACATTGAGAAAATAATTTGCTCAGGTGGTTTCAATTGGGGTTACTGTCCGATACAAAATGAGTCTTTCTTCAAACAGATGGCTTATTCCCTCCCATACAAAGATGCAGTCGTCATTTTCAAAGACATGTCATCAGACGAGTGGCCGAAGAATCTTGTCTATACAATACGTATGAAAAGGGAATTTGACACGGACCTCATATATCCTAAGGACGGGAGGCTGATCCCGCATTCGGCTTTTAGCTTTGAATACAGACAATTCACCGCTCTACAGTGGACGATCGACACCAGTTACATAGAGGTGCTGACCGGGAAAGACATTAATATAGACATGTCCATGCAAGAGTTCCCGTATTATTCGTGGAAGAACAACGACCCGAATATAACGACGGGTATAGCAAGCATCTGTCAGCTGTCTCTGCTGCTGGTGTTCGTGTTCCTCATGTCGAGACTTTTGAACGAGCGAGCGACCGGCATACAGGTAAGTGCACTCGCCACACTGACCTTCGACCCACAATACGTGGCGTCGGTGTCGGTGATCTCGTACGGGGTGCTGGCATACCCGATACACGCGCTGCGGGGGTTGACCATGCCCGGCGCGCTGAGGCTGCTGACGGGGCTGCTGCCGCACGTGCCGCTCGCCTGGCTGCTGGACGAGCTGAGCGTCTTGGACGGAAACGGTGAGTCGATCACAGTGTCGTCGATAATGAAGTCCCACACGGCCGTCAGCTACTCCGTGTTCGTGAGCCATCTGATGATGCTGGCCCAGATCCTAATATTCTTCTTCCTGAACTGGTATCTGTCTCTGGTCAGACCCGGAAAGTACGGACAAGCTTTACCCTGGTACTTCTTGTTTAAGAAACAATACTGGTCGAAGAACGAAATAGGGCCCAAGTTCGACTCGGACGCCGAGGAGCAGGTGCCGATAGTCAACGACAAGAAGTACTTCGAGGAGCCGCCGCAGAACGCCGAGGTTGGCATCCGGATCTGCAACGTGTCCAAGGTGTTCCAGAATCAGAAAGCCCTCGACAACGTGTCGCTGGATGTGTACAAGGGCGAGATCACCGTGCTGCTGGGACACAACGGCGCCGGCAAGACCACCCTCATGTCCATCATAACCGGTATGATGAGCGCGACCGAGGGTAAGGTGTACGTGAACGGCACGGAGACTGCCTCCCAGCAGAGGGAAGTCCGGAAGCACCTCGGGCTCTGCCCCCAGCACAACCTGTTCTTCCCGGACCTCACCGTGCTCGAACACGTCATGTTCTTCACTATGCTCAGGGGAACATCCTTCAGAGAAGCGAAAGCGTCTTCGAAAGCTCTTCTCGAACAGTTGGGTATCGCGGATAAAGCGAACAGCAACAGCTCCGAGCTGTCCGGCGGCATGATGAGGAGGCTGCAGCTGGCGTGCGCGCTCGCCGGCGACGCGGACGTCCTCATCCTGGACGAGCCCACGTCGGGGCTGGACGTGGAGACCAGGAGGAGCCTGTGGGACCTGTTGCTTAGCGTGCGAGGGTCGCGCACCGTGCTGCTGTCCACGCACTTCATGGAGGAGGCGGACGCGCTGGGTCACCGCGCCGCCGCGCTGCACCACGGCCGGCTGCGCTGCCACGCCTCCACCATGTACCTCAAGAAGGCCATCGGTACGGGATATCGGCTGTCGTTCACGACGATCGGGCTGCCCAACGAGGCGGCCATCACCGCGGCCGTCGCGTCGCTGGTCCCCGAAGTGACCCTCAAGGAGAAGTCGCTGAACACGCTCGCGTACAGTCTGCCGGCCGCGCACGCCCACAGGTTCCCGGACCTCTTCCTGGCGTTAGAGTCGAACCGATCTAAATTGGGCATCGACTCCATCGGCGTGGGCATCTCTACGCTGGAGGAAGTATTCCTGAAACTTTGCAGCGATGTCGACACGATCTTCGCCGACGCCAATGGTGACACCAGCGAAACTGCGGACCACTACCAGGAGCCGCAGAGTAAGAGGCTGACCGGCTTCCCCCTGTACCTCAGACAATTCAATGTCCTAATGAAAAGGCAGTTCAACTACATAATGTCCAAGAAACTCTCATTTTTCTTATTGCAAGTCCTGATACCTATGCTAGTGATCGGCCTGGTCACGGAGTCCGTGAACCACGACTACGGGTCCGCGCGGGCCGACGTCAGCGCGCCCATGACCCTCGACCTGTACAAGGACATCGACGGCCTCAAAGCTTTGTACAACGTGAACCAAGAGGGAGTCAACTTCAAAGCGATCACTAACGCCTACCCGCACGTCAAGTTTGAGGAAAATACAGACATCGTCAATACAACACTGGGCTACGCCAAGGGTGATCCAATGAAGTACATTAAATACGTTCTGGGTGTTGAACTTAATTCCACACATGCAAAGGCATTGTACACGACGACAATCCGGCACGCCGCTCCGATATCGGTGAACGTCCTGACGAACCTGCTGGCGACGCTGCACGCGCCGGCGGCGGGCGCGCGCACGCTCACCGCCGTCAACGAGCCCGTGCGCGCGGAGCTGGCGGCCGCACCCTCCTCCGCGCACTCCTCCGCGCCCTCCGCCAAGGACACTAAACAAGTCTTCGTCGTCCTCCTTTGGATATTTTTAGTGGTTTTCACGATTCTATCGACGACCATAAACGCGGTGTCGCTGCCGTGTGCGGAGCGGGAGTCGGGCGCGCGGCACACGCACGTCATGTCGGGCTGCCCGCCGGAGCTGCACTGGGCCTCCACGCTGCTGTTCCACCTGGCCGTCTGCACCGCGGCGCTGGTCGTCCCCACGCTGGTCATCGCGGCCACCGTCGAACGAGACCAGACCATCAACCAGCCTGGCTTCTTGCTAACGTTCTTCCTAATCTTGGAGCTCGGCGCTATGGCTTTCTTCGCGTTAATATATTTAGTGAGCTTCCACTTCAACGAGACGTCGGCCACTATCGTGCTATCCGCCATCGTTATTATATTCGGCATCTTCACGCCCTCAGTGAGCGTCATCTTCACGATCCTCGATGATGCGAAGGGTGTTACCTACTACGTGTTCTCGGTGATCAACTACGTGGTCCCGCCTCACACCGTGATGGTGGCGAGCGTGCTGGCGGGCATGCGGGCCAGCCTGGTGCTCCTTTCGGAGCGGGGCTGGCTGAACGGCTGCTTCGACGCGCTCATGAACCGCGCCTACCCCGCCGCGCCCCCCGCCGCCTCCCCCTCCGACCTCGTGCGCGCCGAGGCCGCTTACGTCAGCAAGGCGATCACACTGCCAAGCAACCAAATCAAGGACGTTCTGTTAGCGGACAACCTGCACAAGAGGTACCCCAAGATCTTCGGCAAGTCCTGCAACGCCGTCAAAGGAGTCAGTTTCTCGGTTAAGAAAGGAGAATGCTTTGGCCTCCTCGGCGTGAACGGAGCCGGCAAGTCTACCACCTTCAAGATGCTGACGGCCGAGGAGTGCGCCACTCGAGGCAACATTTTCGCGAACGGCTACCACCTGAAGCGCAGCGTCGGACCGTACCTCCGCTCCCTCGGCTACTGCCCACAATTCTTCGGGCTGGACGACTTCCTGACCGGCGCCCAGAACCTGGCCTTGCTGCTGACCCTGCGCGGACTCGACGTCGTCGACGTGAACGCCGAGGTCGCGTCCTGGATACAGATCGTAGGGCTGGAGAAGTACATGCACCGGCCCGTGTCGGGCTACAGCGGCGGCTGCAAGCGGCGGCTGGCGGCGGGCGCGGCGCTGGCGGCGGGCGCGGCCGTCACGCTGCTGGACGAGCCCACCGCGGGCGTGGACGTGGCCGCGCGCCGCCGCGTGTGGGCCGCGCTGCGCCGCGCGCTGCACCGGGGACGCGCCGTCGTCATCTCCTCGCACAGCATGGACGAGATGGACGCGCTGTGCTCGTCGATAGCCATCCTGTCGGCGGGCGGCGTGCGCGCGCTGGGCTCGGGCGCCGCACTGCGCGCCGCGCACGCCGCCGGACACGCGCTGCTGCTCAAGATCGCGCACGCACCTGCCGCAGACGAAGTGGACGGTGCCAAGGGTGAGCTGGACCGGCTGAAGGGCGTGCTGCACCAGTCCTTCGACTGCACCCTCAAGGACGAGCACAAGACGATGCTGCACTACCATATAAACGAAACAATGAAATATTCGGAACTCTTCACTCAGCTCGAGGAACTAAAGGCCAACTTCCCCGGGCTCGTGGAGGACTATTCGGTCACGGAGACCACCCTGGAAGAGGTGTTCCTGTCTTTCGCCAAAGAACAAAATGAACCCGCGTCCGTATGA
Protein sequence (1517 aa)
MDCHSVKVLMWKHLTVRMRRYFHTLVELLSPIALILLFSALNIVKTPPDHVVSSAQYNPEYHSKNFERPNCIYYYPETNLTKTLMDQVAKKFHIEKIICSGGFNWGYCPIQNESFFKQMAYSLPYKDAVVIFKDMSSDEWPKNLVYTIRMKREFDTDLIYPKDGRLIPHSAFSFEYRQFTALQWTIDTSYIEVLTGKDINIDMSMQEFPYYSWKNNDPNITTGIASICQLSLLLVFVFLMSRLLNERATGIQVSALATLTFDPQYVASVSVISYGVLAYPIHALRGLTMPGALRLLTGLLPHVPLAWLLDELSVLDGNGESITVSSIMKSHTAVSYSVFVSHLMMLAQILIFFFLNWYLSLVRPGKYGQALPWYFLFKKQYWSKNEIGPKFDSDAEEQVPIVNDKKYFEEPPQNAEVGIRICNVSKVFQNQKALDNVSLDVYKGEITVLLGHNGAGKTTLMSIITGMMSATEGKVYVNGTETASQQREVRKHLGLCPQHNLFFPDLTVLEHVMFFTMLRGTSFREAKASSKALLEQLGIADKANSNSSELSGGMMRRLQLACALAGDADVLILDEPTSGLDVETRRSLWDLLLSVRGSRTVLLSTHFMEEADALGHRAAALHHGRLRCHASTMYLKKAIGTGYRLSFTTIGLPNEAAITAAVASLVPEVTLKEKSLNTLAYSLPAAHAHRFPDLFLALESNRSKLGIDSIGVGISTLEEVFLKLCSDVDTIFADANGDTSETADHYQEPQSKRLTGFPLYLRQFNVLMKRQFNYIMSKKLSFFLLQVLIPMLVIGLVTESVNHDYGSARADVSAPMTLDLYKDIDGLKALYNVNQEGVNFKAITNAYPHVKFEENTDIVNTTLGYAKGDPMKYIKYVLGVELNSTHAKALYTTTIRHAAPISVNVLTNLLATLHAPAAGARTLTAVNEPVRAELAAAPSSAHSSAPSAKDTKQVFVVLLWIFLVVFTILSTTINAVSLPCAERESGARHTHVMSGCPPELHWASTLLFHLAVCTAALVVPTLVIAATVERDQTINQPGFLLTFFLILELGAMAFFALIYLVSFHFNETSATIVLSAIVIIFGIFTPSVSVIFTILDDAKGVTYYVFSVINYVVPPHTVMVASVLAGMRASLVLLSERGWLNGCFDALMNRAYPAAPPAASPSDLVRAEAAYVSKAITLPSNQIKDVLLADNLHKRYPKIFGKSCNAVKGVSFSVKKGECFGLLGVNGAGKSTTFKMLTAEECATRGNIFANGYHLKRSVGPYLRSLGYCPQFFGLDDFLTGAQNLALLLTLRGLDVVDVNAEVASWIQIVGLEKYMHRPVSGYSGGCKRRLAAGAALAAGAAVTLLDEPTAGVDVAARRRVWAALRRALHRGRAVVISSHSMDEMDALCSSIAILSAGGVRALGSGAALRAAHAAGHALLLKIAHAPAADEVDGAKGELDRLKGVLHQSFDCTLKDEHKTMLHYHINETMKYSELFTQLEELKANFPGLVEDYSVTETTLEEVFLSFAKEQNEPASV
Domains and motifs
| Database | ID | Description | Start | End | Evalue | InterPro ID |
|---|---|---|---|---|---|---|
| PANTHER | PTHR19229 | - | 5 | 1347 | 5.7e-271 | IPR026082 |
| Gene3D | 3.40.50.300 | - | 409 | 641 | 7.5e-66 | - |
| SUPERFAMILY | SSF52540 | - | 410 | 636 | 2.8e-60 | IPR027417 |
| CDD | cd03263 | ABC_subfamily_A | 419 | 636 | 1.0e-94 | - |
| ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. | 419 | 648 | 22.609 | IPR003439 |
| Pfam | PF00005 | ABC transporter | 434 | 578 | 1.6e-33 | IPR003439 |
| SMART | SM00382 | - | 443 | 627 | 1.3e-13 | IPR003593 |
| ProSitePatterns | PS00211 | ABC transporters family signature. | 550 | 564 | - | IPR017871 |
| Pfam | PF12698 | ABC-2 family transporter protein | 781 | 1109 | 2.3e-17 | - |
| Gene3D | 3.40.50.300 | - | 1177 | 1422 | 9.9e-54 | - |
| SUPERFAMILY | SSF52540 | - | 1186 | 1411 | 7.6e-50 | IPR027417 |
| CDD | cd03263 | ABC_subfamily_A | 1187 | 1405 | 2.1e-65 | - |
| ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. | 1187 | 1422 | 17.827 | IPR003439 |
| Pfam | PF00005 | ABC transporter | 1208 | 1351 | 2.8e-21 | IPR003439 |
| SMART | SM00382 | - | 1216 | 1398 | 0.47 | IPR003593 |
| PANTHER | PTHR19229 | - | 1323 | 1512 | 5.7e-271 | IPR026082 |
InterPro assignment
| InterPro ID | InterPro description |
|---|---|
| IPR003439 | ABC transporter-like |
| IPR003593 | AAA+ ATPase domain |
| IPR017871 | ABC transporter, conserved site |
| IPR026082 | ABC transporter A |
| IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Gene ontology (GO) assignment
| GO category | GO ID | GO description |
|---|---|---|
| molecular function | GO:0005524 | ATP binding |
| cellular component | GO:0016021 | integral component of membrane |
| molecular function | GO:0016887 | ATPase activity |
| molecular function | GO:0042626 | ATPase-coupled transmembrane transporter activity |
| biological process | GO:0055085 | transmembrane transport |
| Species | Accession |
|---|---|
| Danaus plexippus | DPOGS202910 |
| Heliconius melpomene | HMEL032331g1.t1 |
| Manduca sexta | XP_030036282.1 |
| Plutella xylostella | g36192.t1 g38990.t1 |
| Spodoptera frugiperda (corn) | GSSPFG00026303001-PA |
| Spodoptera frugiperda (rice) | SFRICE027532-PA SFRICE039628-PA |
| Acyrthosiphon pisum | XP_003246127.1 XP_029344491.1 XP_029344492.1 |
| Aedes aegypti | AAEL021738-PA AAEL021738-PB |
| Anopheles gambiae | - |
| Apis mellifera | XP_003249939.3 XP_006561880.2 |
| Drosophila melanogaster | FBpp0110124 FBpp0288866 FBpp0309770 |
| Tribolium castaneum | XP_008195056.1 XP_008195057.1 |
| Homo sapiens | NP_001080.2 |
| Mus musculus | NP_671752.2 XP_006533128.1 |