Position
| Chromosome | chr19 |
| Start | 11723558 |
| End | 11736493 |
| Strand | + |
view in Gbrowse: chr19:11723558..11736493
Most similar sequence in NCBI nr database
| Accession | Description | E-value | Score |
|---|
| XP_004922476.1 | ATP-binding cassette sub-family B member 8, mitochondrial | 0.0 | 1429 |
ORF sequence (2085 bp)
ATGTGGTATATGTTACAGAATCACTTATTTTGTCTCACAAGACAAAGGTTCCTGGCTTCAAAAAGTAATAAATACTTCACTAATATAGTAAAAAACAAGCCATCAGACGCTTTAAATCGATATATATCACAGTTAAAGACTCGTGGAAAAAGTTCAAAGTCTGGAGAATCATTGCCTTGCAGTCCATGGAAATTGTGTACAGGAGTTAGTTTAGCTATTGGCGCTCGGTATTTTCTATATAGGAGTCCAGTATTTTGTAAAGCAGTTCAGACTTCGAGAGTAATACAGAGAAGGCCGAATTTCCAAGAGGATACCGCTAAATTTGATTGGGAAAAATTATTGAACTATTTAAAACCTCATAAATGGCTCCTTATAGCTGCTGTTGGTTCTGCGTTAGCTGTGGCATTCCTAAATGTGTACATCCCAGCTATGCTCGGTGTCATCGTGAATGTTCTAGCAGGAATAAGGAATAATCCGGCTGCTGATTTCATTGACGAGATCAAGATGCCGGCATTTAAATTGATTTCATTGTATGTTGGACAGGCAGCTTTTACGTTTTTCTACATTCACTTGCTGTCACAAGTGGGAGAAAAAGTGGCCACTCAAATGAAACAAGATCTATTTGTATCTATTCTAAGACAGGATATAGAATTTTTTGATAAAGAAAGAACTGGGGAATTAGTTAATAGGTTAACAGTGGACGTACAAGACTTCAAAAGCTCTTTCAAACAGACCATATCGGGAGGTCTTAGAGCTATTACGCAGGTGGTGGGTTCTGCGGTGAGCCTCTTAGTCATATCCCCACATTTGACAGGGCTGACGATGATCTGCGTCCCGTCAGTTGTTATCGGAGGCACCTTCATTGGTTCGCTGTTGAGGAAATTGTCCAGGGAAGCTCAAACTCAGATAGAAAAGGCGACGTTGGTGGCGGAGGAAGCACTCTCCAACATGCGGACGGTTCGAGCCTTCGCCGCCGAAGACAGCGAGGCGCAGATGTTTGCCAAGGAGTGTGACGAGGCCGCCCAGCTCAGCATGGAGCTGGGACTCGGCATCGGATTGTTTCAGGCCGGGACTAACCTGTTCTTGAATGGAATGGTGCTCGGCACTATGTTCCTCGGCGGTCATTTGATGTCGACCGGGCAGATGTCGGCGGGAGACGTGATGGCGTTCCTGGTGAACGCGCAGACTGTGCAGCGCTCGGTGGCGCAGCTGTCTCTGCTGTTCGGCTCCGTCGTTAAGGGGATCAGCGCCGGCGGTCGGGTGTTCGAGTACATCAATAAGAAACCCGCAATGGACACGTCCGGTACTAAGTATATAAAGTACCACGAGTTTCACGGCGACATCGAGTTTAAGAACGTCACATTCGCCTATCCCACAAGACCGGAGGCTGTGATATTGAAGGATTTCAATCTTAAAATACCTGCTGGCAAGACGGTCGCCATAGTCGGCACATCTGGCAACGGGAAGTCTACTATCGCTGCTCTGTTGGAAAGGTTCTACGACGTGAACGAAGGCCAAGTGTCGATAGATGGCGTTGTCTTGCGCGAGTTCGACGGCAAGTGGCTCCGCGGGAGGGCGCTAGGTCTGATCGGCCAGGAGCCGGTCCTGTTCGCCACCACGGTCCGGGAGAACATCCGGTACGGGAGACCAGAGGCCACTGATGCTGAGGTGATGCAGGCGGCTACGATAGCCAATGCTCATGAGTTCATACAGTCGTTCCCGGAGGGGTACGATACTCTGGTCGGCGAGAGGGGGATGGCTCTGAGCGGGGGACAGAAGCAGCGAGTCGCCATCGCCAGAGCCGTGCTGAAGAATCCACCGGTTATAATACTGGACGAGGCCACCAGCGCTCTTGATTCCGCGAGCGAGAAGGTCGTACAGAAGGCGCTGGAGACGGCGGCCAAGGGTCGGACCGTGCTGGTGATAGCCCACAGGCTATCCACGGTCATCAATGCCGATCTGATCGTCGTATTAAACAAGGGGAAGATTGTTGAGATGGGAAATCATGAACAATTGAAGAAATTGAAGGGTTTTTATTGGAATCTTATAAAGCAACAGGATCAAGATCTAGAGCAATCGAGATGA
Protein sequence (694 aa)
MWYMLQNHLFCLTRQRFLASKSNKYFTNIVKNKPSDALNRYISQLKTRGKSSKSGESLPCSPWKLCTGVSLAIGARYFLYRSPVFCKAVQTSRVIQRRPNFQEDTAKFDWEKLLNYLKPHKWLLIAAVGSALAVAFLNVYIPAMLGVIVNVLAGIRNNPAADFIDEIKMPAFKLISLYVGQAAFTFFYIHLLSQVGEKVATQMKQDLFVSILRQDIEFFDKERTGELVNRLTVDVQDFKSSFKQTISGGLRAITQVVGSAVSLLVISPHLTGLTMICVPSVVIGGTFIGSLLRKLSREAQTQIEKATLVAEEALSNMRTVRAFAAEDSEAQMFAKECDEAAQLSMELGLGIGLFQAGTNLFLNGMVLGTMFLGGHLMSTGQMSAGDVMAFLVNAQTVQRSVAQLSLLFGSVVKGISAGGRVFEYINKKPAMDTSGTKYIKYHEFHGDIEFKNVTFAYPTRPEAVILKDFNLKIPAGKTVAIVGTSGNGKSTIAALLERFYDVNEGQVSIDGVVLREFDGKWLRGRALGLIGQEPVLFATTVRENIRYGRPEATDAEVMQAATIANAHEFIQSFPEGYDTLVGERGMALSGGQKQRVAIARAVLKNPPVIILDEATSALDSASEKVVQKALETAAKGRTVLVIAHRLSTVINADLIVVLNKGKIVEMGNHEQLKKLKGFYWNLIKQQDQDLEQSR
Domains and motifs
| Database | ID | Description | Start | End | Evalue | InterPro ID |
|---|
| PANTHER | PTHR24221 | - |
86 | 687 | 0.0 |
IPR039421 |
| PANTHER | PTHR24221:SF167 | - |
86 | 687 | 0.0 |
- |
| Gene3D | 1.20.1560.10 | - |
106 | 438 | 1.2e-87 |
IPR036640 |
| SUPERFAMILY | SSF90123 | - |
112 | 429 | 6.8e-68 |
IPR036640 |
| Pfam | PF00664 | ABC transporter transmembrane region |
125 | 400 | 1.3e-53 |
IPR011527 |
| ProSiteProfiles | PS50929 | ABC transporter integral membrane type-1 fused domain profile. |
125 | 413 | 49.476 |
IPR011527 |
| CDD | cd18574 | ABC_6TM_ABCB8_like |
127 | 421 | 7.1e-159 |
- |
| SUPERFAMILY | SSF52540 | - |
438 | 686 | 2.1e-90 |
IPR027417 |
| Gene3D | 3.40.50.300 | - |
439 | 693 | 2.1e-93 |
- |
| CDD | cd03249 | ABC_MTABC3_MDL1_MDL2 |
448 | 686 | 2.2e-139 |
- |
| ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. |
448 | 685 | 24.343 |
IPR003439 |
| Pfam | PF00005 | ABC transporter |
466 | 616 | 9.0e-30 |
IPR003439 |
| SMART | SM00382 | - |
475 | 662 | 4.8e-15 |
IPR003593 |
| ProSitePatterns | PS00211 | ABC transporters family signature. |
588 | 602 | - |
IPR017871 |
InterPro assignment
| InterPro ID | InterPro description |
|---|
| IPR003439 | ABC transporter-like |
| IPR003593 | AAA+ ATPase domain |
| IPR011527 | ABC transporter type 1, transmembrane domain |
| IPR017871 | ABC transporter, conserved site |
| IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| IPR036640 | ABC transporter type 1, transmembrane domain superfamily |
| IPR039421 | Type I protein exporter |
Gene ontology (GO) assignment
| GO category | GO ID | GO description |
|---|
| molecular function | GO:0005524 | ATP binding |
| cellular component | GO:0016021 | integral component of membrane |
| molecular function | GO:0016887 | ATPase activity |
| molecular function | GO:0042626 | ATPase-coupled transmembrane transporter activity |
| biological process | GO:0055085 | transmembrane transport |