Position
| Chromosome | chr18 |
| Start | 9248808 |
| End | 9258869 |
| Strand | + |
view in Gbrowse: chr18:9248808..9258869
Most similar sequence in NCBI nr database
| Accession | Description | E-value | Score |
|---|
| XP_028027400.1 | ATP-binding cassette sub-family B member 10, mitochondrial | 0.0 | 1426 |
ORF sequence (2094 bp)
ATGTTACGACTTCTTCAAAATTTGGAACTGAAAATATCTAGTAGGCATACAAATTTATGGCACAAAATTCAATACAAAAAATATTTATGTTATCAGTGTGGTGTCAGGTTTTATAGTCACAAACCGAAAACACAAAATTGTGATAGGACTTTTCTTAATAAAAATAGGGCATTTCATTTTAAATTAAGGTATTACACTAGCCAGATAGATGCACAAAAAAATGAAGAACCCATTGAAAATTTGAAAAATAAAACCACATTAGTCACGGGCAAGAAAATTAATGTAAAATTAAAAACTTCAGAACTAAAACGATTACTTGGACTGGCCGAACCTGAAAAATGGACATTAACTGGTGCCATTGGTTTCCTAATAGTGTCATCAAGTGTGACGATGGCCGTACCATTTTCCCTTGGCAAAGTACTTGATATAATATACAATAGTACAAGTGACTTAGCTGCTGCTAGAGAAAAGCTCGATGCATTATGTCTGATGCTCTGTGGGGTATTCTTAATAGGAGGCCTGTGTAACTTTGGAAGAGTTTACCTGATGTCCATATCTGGGCAAAGAATGACTCAGGCTCTCCGGAAACAAGTTTATGGTGCGATTTTAAAACAAGAAACGGCGTGGTTTGGAAGAACATCAACAGGGGAATTAGTTAACAGATTATCTGCAGATACACAGCTTGTGGGCCGTAATCTCAGTCAAAATGTTAGCGACGGCCTTAGGTCTTTGTTTATGGTTGGAGCTGGAACAGGAATGATGTTCTACATGTCGCCTTCATTGGCTTTGATCGGACTGTGTGTGGTACCGCCTGTTTCAATGTTGGCTGCCATATATGGACGGTTCGTCCGTGGGATCACAAGGGAGTTGCAAGATTCACTTGCGGAAACGAGCGAACTTGCTGAAGAAAAAATATCAAACATAAAGACTGTGAAAGCATTTAGCAAGGAGCCTAAGGAATGCGAATCTTATGCAAAGAGGATTGAAAATTTACTAAATTTGGCTTACAAGGAGTCATTAGCGGTCGGCAGTTTCTACGGTTTGACTGGCCTCGCGGGAAACACTATAATAATATTAGTTTTATATTACGGAGGAGGCATGGTGGCGACAGAGCAACTCACAGTCGGTAACTTGACATCGTTCCTACTGTACGCTGCGTATGTGGGGATCAGTATTGGTGGACTGAGTAGTTTCTACACGGAACTAAATAAGGGCATGGGAGCCGCGACCAGACTGTGGGAGATCATTGATAGGGAGCCCAAAATTCCTGTCACAGGAGGCTTAATACCGAAAGAGAAACCGAACGGCGAAATAATATTAGAAAAAGTACATTTCTCCTACAACGATGCGCCTCTAATACGAGGACTGGATCTTCATTTGAGACCCGGGAAGTCAGTTGCGCTTGTCGGTAGATCTGGCTGCGGGAAGAGCACCATAGCATCGCTTATATTGAGACTCTACGACCCGGATAAGGGTAGAGTTTTACTCGATGGAGTCGACATAAGGGAATTAGATCCGATGTGGTTGAGAAGTCTGATCGGCTACGTTGGTCAAGAACCGGTGTTGTTCAGTGGAACAGTCAAGGAAAATATTTTGTACGGAGCTTTAGATGAAAACGAAGAAGTACAAAATGAAAAGGACGAGCCAGCGTGGATGGTGGCAGCTCGCACTGCTCATCTGCACGAGCTAGTGACCGGCACCCGCCAAGGCTGGGACAGAGAGGTAGGCGCCGGCGGTAGTCAGCTGAGCGGGGGACAGAAACAAAGGGTGGCCATTGCACGGGCCATTGTTAAGAATCCGAAAATCTTGATCCTCGACGAAGCCACATCAGCGCTAGATACGTATTCGGAGTACTTAGTTGATAAAGCTTTAAAAGAGATCAGTAAGTCTAGAACGGTTCTGACCATAGCGCACAGGTTGAGCACGATACAGTCCGCGGACGAGGTCGCTGTGCTCGAGAATGGAGTTGTAGTTGAGACGGGACCTTACGCCGAGCTAGTAGCCAAACCGGACGGCCTCTTTAGGGAGTTGATAACGCATCAAACGTTTACCGCGAAATCGAGAGACAAAAAGGATATGCAGAAAAGTCAATGA
Protein sequence (697 aa)
MLRLLQNLELKISSRHTNLWHKIQYKKYLCYQCGVRFYSHKPKTQNCDRTFLNKNRAFHFKLRYYTSQIDAQKNEEPIENLKNKTTLVTGKKINVKLKTSELKRLLGLAEPEKWTLTGAIGFLIVSSSVTMAVPFSLGKVLDIIYNSTSDLAAAREKLDALCLMLCGVFLIGGLCNFGRVYLMSISGQRMTQALRKQVYGAILKQETAWFGRTSTGELVNRLSADTQLVGRNLSQNVSDGLRSLFMVGAGTGMMFYMSPSLALIGLCVVPPVSMLAAIYGRFVRGITRELQDSLAETSELAEEKISNIKTVKAFSKEPKECESYAKRIENLLNLAYKESLAVGSFYGLTGLAGNTIIILVLYYGGGMVATEQLTVGNLTSFLLYAAYVGISIGGLSSFYTELNKGMGAATRLWEIIDREPKIPVTGGLIPKEKPNGEIILEKVHFSYNDAPLIRGLDLHLRPGKSVALVGRSGCGKSTIASLILRLYDPDKGRVLLDGVDIRELDPMWLRSLIGYVGQEPVLFSGTVKENILYGALDENEEVQNEKDEPAWMVAARTAHLHELVTGTRQGWDREVGAGGSQLSGGQKQRVAIARAIVKNPKILILDEATSALDTYSEYLVDKALKEISKSRTVLTIAHRLSTIQSADEVAVLENGVVVETGPYAELVAKPDGLFRELITHQTFTAKSRDKKDMQKSQ
Domains and motifs
| Database | ID | Description | Start | End | Evalue | InterPro ID |
|---|
| PIRSF | PIRSF002773 | - |
4 | 697 | 1.9e-226 |
- |
| PANTHER | PTHR24221 | - |
76 | 686 | 3.3e-190 |
IPR039421 |
| PANTHER | PTHR24221:SF446 | - |
76 | 686 | 3.3e-190 |
IPR030260 |
| Gene3D | 1.20.1560.10 | - |
97 | 430 | 4.7e-112 |
IPR036640 |
| SUPERFAMILY | SSF90123 | - |
103 | 420 | 6.5e-76 |
IPR036640 |
| ProSiteProfiles | PS50929 | ABC transporter integral membrane type-1 fused domain profile. |
118 | 404 | 54.49 |
IPR011527 |
| CDD | cd18573 | ABC_6TM_ABCB10_like |
119 | 412 | 1.3e-152 |
- |
| Pfam | PF00664 | ABC transporter transmembrane region |
119 | 388 | 8.5e-65 |
IPR011527 |
| SUPERFAMILY | SSF52540 | - |
429 | 681 | 4.4e-80 |
IPR027417 |
| Gene3D | 3.40.50.300 | - |
431 | 697 | 6.3e-87 |
- |
| ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. |
438 | 679 | 24.957 |
IPR003439 |
| Pfam | PF00005 | ABC transporter |
455 | 610 | 5.7e-35 |
IPR003439 |
| SMART | SM00382 | - |
462 | 662 | 4.9e-20 |
IPR003593 |
| ProSitePatterns | PS00211 | ABC transporters family signature. |
582 | 596 | - |
IPR017871 |
InterPro assignment
| InterPro ID | InterPro description |
|---|
| IPR003439 | ABC transporter-like |
| IPR003593 | AAA+ ATPase domain |
| IPR011527 | ABC transporter type 1, transmembrane domain |
| IPR017871 | ABC transporter, conserved site |
| IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| IPR030260 | ATP-binding cassette subfamily B member 10-like |
| IPR036640 | ABC transporter type 1, transmembrane domain superfamily |
| IPR039421 | Type I protein exporter |
Gene ontology (GO) assignment
| GO category | GO ID | GO description |
|---|
| molecular function | GO:0005524 | ATP binding |
| cellular component | GO:0016021 | integral component of membrane |
| molecular function | GO:0016887 | ATPase activity |
| molecular function | GO:0042626 | ATPase-coupled transmembrane transporter activity |
| biological process | GO:0055085 | transmembrane transport |