Position
| Chromosome | chr17 |
| Start | 7613006 |
| End | 7644573 |
| Strand | - |
view in Gbrowse: chr17:7613006..7644573
Most similar sequence in NCBI nr database
| Accession | Description | E-value | Score |
|---|---|---|---|
| XP_012546914.1 | ATP-binding cassette sub-family A member 1 | 0.0 | 3586 |
ORF sequence (5190 bp)
ATGAGACCTCAGAGAAAAGAAGCCGGGGCGTTTACAAAATTTAGATTACTGATATGGAAAAATTTAATACAACAATGGAGACACCGCTTACAAACAGTTGTAGAATTATTACTGCCTGTTATAACTATGACACTTATACTAATCCTAAGGTGGCAAGTTGAACCAACAAATCGGGAAACAATCAGGTACCCAGAAATATCGTCACATAGCCTTCAATACTCGTCAATGATAATCGCAGGCCTGAACACAACAAGAATGTCAATAGCCTATTCACCGACTAGTCCCGAACTTGAAGACGTTGTGCGAAGTAGCGTCGCTAATCTGTTGCTTTTAAATATTAAGCATATAATAAATGATACAGAAACAATCATGCCAGAAGTAGAGCTACCGCCCGACATAAATTGGAATGATAGTGCTATTTATGAAATTATCAAACGCATCTTGAGAGTAGATGCATATGATAATAGTAACGCTTTAAGGGGTATATACGCTCTTGAAGAAATAACACGTGAAGTTGTACTGGCTGTGGAATTTAATGATTCGCTCCTTGGGGCAACGGAGTTGTCAAATAACTTATCATTTGCATTGAGATTTCCCGAGAGGCCTAGGTTAAACTCATTTTACGCACAAGGTGGTCGCTCTTGGAGAACAGATGATGTATTTCCTGTATTTGAAAATCCAGGACCGAGATTTCCTTTGTCGTGGGAAGGTGGCAATGACCCAGGATACGTAAATGAAATGTTTATAGCATTTCAAAGCTGTATTTCGGCGGAACTTGTATCTAGATTAACGGGGAAGCCGGAATTAAAATCGTTTTCTGTGAACATACAAAGATACCCGCACCCGCCCTATGTGGACGATTTAGCAGTAGAAGCATTGCAAATGATTTTTCCGATGTTCATATTGTTGAGTTTTAGTTATTCAGCCGTGAATTTAGTAAGAGCAGTTACTTTAGAAAAGGAATTGCAGTTAAAGGAAACGATGAAAATAATGGGAATATCCACGTGGCTCCATTGGACCGCATGGTTCTTCAAGCAATTTATTTATTTAATGATAAGTGCAATCCTTATCATTGTCCTCTTAAAGGTTAGTTGGTTTACAAATGCGGACGGATTCAGCGGATACGCGGTCTTCACGAACACTCCTTGGACCGTTTTGCTTTTTTTTCTAGCGCTTTACCTGATTTGTTCAATCTTTTTTTGTTTTATGATCAGCGGCTTCTTTTCTAAAGGTAGTACATCAGCATTGTTCGGAGGCGTTATTTGGGTACTGGTGTATATCCCAGCATTACTGCTTTCAATGGATAACAATATGTCCATTGTAACACAGGTCATCACCTGCCTCAGTGTAAACTGCGCCATGTCTTACGGCTTTCAGTTATTGTTCGGAAAAGAGAGTATTGGTGGTATGCAATGGGGAGATTTTATGGCATCACCATCATCGGACTCTTCGCGATTCGTTTTTGGGCATGTAATTCTGATGCTGGTATTTGATTCCGTGCTGTATATGTTAATAGCCCTGTATTTAGAGCAAGTCTTGCCTGGACCCTTCGGTTTACCAAAGCCATGGTATTTTCCTATACAAAAGAGCTTTTGGTTTCCTAACAACGAAGAATCTAAAAATGGCATTATAATTGAACACGCAATTTCTAATGACGATGTTATTTTGGAAAAGGATCCGGAAAATCTCACAGTTGGTGTTAGAATGAATAATTTAACTAAAATATTTGGCGCAAACGTAGCAGTGAACCAATTGACTTTGAACATTTTTGATAACCAAATAACTGTATTACTTGGTCACAACGGTGCCGGTAAATCAACAACCATGTCTATGCTAACAGGAAACATGAAAGCTACCCGTGGCTCAGTAACATTAGCGGGCTATGATATTCAAACACAAGTTAAAGCGGCTAGAGCTCATCTCGGCTTTTGCCCGCAACACAATGTACTTTTCAACGATTTAACTGTCAAAGAACATTTGGAATTCTTCGCCAGACTTAAAGGATTTTCGGGAAAAGAACTTTATCAAGAGATAGATTCTTTAATTGAAAAGTTAGAACTTCAAGAAAAGCAAAACTACGTCGCTAATGGATTATCAGGTGGTCAGAAACGTAGATTATGCGTTGGAATAGCCCTGAGTGGTGCCGCTAGCGTGGTATTGCTGGATGAGCCTACATCGGGAATGGATCCGGCTTCAAGACGAGCCCTGTGGGACTTATTGCAAAGAGAGAAACGAGGGCGCTCTATTATCTTAACAACTCATTTCATGGACGAGGCTGATGTTCTCGGTGACCGAGTGGCGATTATGGCTAATGGTCGTCTCCAGTGCGTTGGGACACCATATTTTTTGAAACGCCATTACGGAGTTGGTTACACATTAGTCGTTGTCAAAAAGGAAGGTTTCGACTACACGGCGTGCACCGATCTAATCAATAAATATATACCCGGGATTGCAATTAAAGAAGATCGCGGACCAGAAATAAATTACTCCTTAACAAACATCCAGTCTCATGTATTTGAAGATATGCTTAACGATTTCGAAAAGAATGTTAACAATATTAAATTCAAAGACTATGGCTTGATAGCAACTACTTTAGAAGATGTATTCATGTCAGTGGGTTCTGATGTGGCAACAATAAACTCTGTCAGCGACGATGGAGCTGCAAGTCTTGATCTATCAGGCGATGATAATCTAAAAAATGAATTTTCATCTTTGGAACAATTGACGAAAGAAGGTAAAGTGTCAGGAGCAAGTCTGGTCGGAAAGCACGTGTTAGCAGTTTGGATGAAACTGTTTTTGGTCTGGTTTCGTTCTTGGTGGATGGTACTCCTCCAGTTGGCTGTTCCAATAGTTATGATGAATGCGACGCTGCTGATCGTACAGTTCCTCATTTCGTTCGTTGCCAATATCCAAATAAGGCATTTGTCACTCGAATATGGGTATTCGAGGACCGAGACATTGTTATCATTCAACGGAAGTTCAAGTTCATCCATTGGTGCGTTGGCAAGCAACGCTTACGAAAATATTTTTAAGTCATCTGGCATAGATACCATGGAAATAACAATCGTAGAAGATCAGTCAATCGACGAGTATTATTTAGAAAGGGCATCAGATCCAATTGAAATGGGTGCACTGCGACACAGTGTCCTGACAGGCGCTACATTTTCTGACGACGTCGCGACCGCGTGGTTCAGCAACTTCGCCTACCATGATGTGGCGACTTCATTGGCTTCTGTTTATTCAGCGCTACTTCGAGCCTTCAACTCCACAGCCGAGATCAATGTGTACAATCACCCTATAGAAGCCACATATAAAAATCAAAACGACATGCAACTGTTGGTCACCATGATATCGATGCAGCTCTCCTCCGGCGTGGCCAGCTGTATCGCCATCGTCAGCGCCGTCTTCGTCATGTTTTATATTAAGGAACGTGCGTGTGGTGCTAAGTTACTACAAAAGGCGGCTGGCATCCAGCCCGCTGTACTTTGGGGGAGCGCAGCGGTCTTTGACTGGCTCTTGTTCAGTATTATCTGCATTACCATTGTAATTACATGTGCTGCGTTCGAGGTACAGGGACTATCTACTTTTGTAGAATTGGGACGAATGTACCTTTGCCTGATTGTGTACGGCGCGGCGATGCTACCACTCAACTATCTACTGTCGCATTTATTCGAAGGGCCAGCTTTAGGTTTTGTCGTCATATTCTTCACGAATTGTTTGTTGGGTATGATGGGGCCACAAATAGTTGAGGCTTTGTCGTCTCCGCAACTCAACACTCAAAACGTAGCGGACATACTCGATACGATATTTCAATTTTTCCCGCTCTACAGCCTTGTGACATGTGTCAGGGAATTGAACCAGATAGGTCTGGTGGAGTACTCGTGTATGCGTGGATGCGAGTACATTTCAGTGTTGTTGCCAGACCTCAAGGAATGCACAATGGCGGTCATGTGTGAACATTACTTGGAGTCTTGCTGTGTTCGTGAAAGTCCTTATTTCGAATGGGAAAAACCAGGCGTCCTTCGATATCTGGTCGTGATGTTGGCTACCTGCGGTGTTTTGTGGTTGATCCTTATGACTATCGAGTATCGTTTGTTCCAAAAGGTCTTCATGTTCAGAAAAATACCGCCTCCGATACCGGAGAATACGCTCGATAAGGACGTGGCTGACGAGGCGGAGCATGTCCGGCAGATCAGCAAGCCAGATCTGGCGCGGCACGGACTCGTCGCGAAGAACCTCTCCAAATATTACGGATCGAATCTCGCAGTCGACCAAGTATCTTTCACTGTTAGCGACTCTGAATGTTTCGGTCTGCTCGGAGTGAACGGTGCCGGGAAAACGACCACATTTAAAATGTTGATGGGCGACGAGAACATCTCCAGCGGCGAAGCGTTCGTCAGCGGGTACTCCGTCCAGCAGCGGCTGACTAAAGTGCACAAGAATATCGGCTACTGTCCTCAGTTCGACGCTTTGTTCGGGGAGCTGACTGGGCGCGAAACGCTGCGCCTGTTCTCATTGTTGCGCGGCCTTCGGAACTTCAGCGGCGCGCACGCGGACATCCTCGCGCACTCCCTCGGCTTCCTTAAGCATTTAGATAAAAGAGTGGATCAGTATTCTGGTGGAACAAAAAGGAAGTTAAACACAGCAATAGCTTTCCTAGGAACAACTCGTTTAATTTTCGTTGATGAACCGACAACGGGCGTAGATCCCGCTGCCAAACGACACGTTTGGCGGGCGATGCGCGGCGTGCAGCGCACGGGGCGCGGGGTGGTGCTGACGTCACACAGCATGGAGGAGTGCGAGGCGTTGTGTTCGCGCCTCACGATAATGGTCAACGGCCGGTTCCAGTGTCTCGGCTCACCGCAGCATCTCAAAAACAAATTTTCTCAAGGATTCACTTTGATCATCAAACTGAAGTCAAATGAGGAGACAAATCCGTCATCCAGCAGAAACCAAGAAGAAGCTATTAAAAGTTACGTCACCGCCAATTTCGTCAACCCTAAGATGATGGAGGAGCATCAGGGTCTGATAACATACTATTTGCCGGATCAGACTGTGCCGTGGTCGAAGATGTTCGGTATAATGGAACGAGCGAAACAATCCCTCGACGTTGAAGATTACAGCATCTCTCAGACGACCCTAGAGCAGATATTCTTGCAGTTTACGAAATATCAAAGGGAAGGCTTGTGA
Protein sequence (1729 aa)
MRPQRKEAGAFTKFRLLIWKNLIQQWRHRLQTVVELLLPVITMTLILILRWQVEPTNRETIRYPEISSHSLQYSSMIIAGLNTTRMSIAYSPTSPELEDVVRSSVANLLLLNIKHIINDTETIMPEVELPPDINWNDSAIYEIIKRILRVDAYDNSNALRGIYALEEITREVVLAVEFNDSLLGATELSNNLSFALRFPERPRLNSFYAQGGRSWRTDDVFPVFENPGPRFPLSWEGGNDPGYVNEMFIAFQSCISAELVSRLTGKPELKSFSVNIQRYPHPPYVDDLAVEALQMIFPMFILLSFSYSAVNLVRAVTLEKELQLKETMKIMGISTWLHWTAWFFKQFIYLMISAILIIVLLKVSWFTNADGFSGYAVFTNTPWTVLLFFLALYLICSIFFCFMISGFFSKGSTSALFGGVIWVLVYIPALLLSMDNNMSIVTQVITCLSVNCAMSYGFQLLFGKESIGGMQWGDFMASPSSDSSRFVFGHVILMLVFDSVLYMLIALYLEQVLPGPFGLPKPWYFPIQKSFWFPNNEESKNGIIIEHAISNDDVILEKDPENLTVGVRMNNLTKIFGANVAVNQLTLNIFDNQITVLLGHNGAGKSTTMSMLTGNMKATRGSVTLAGYDIQTQVKAARAHLGFCPQHNVLFNDLTVKEHLEFFARLKGFSGKELYQEIDSLIEKLELQEKQNYVANGLSGGQKRRLCVGIALSGAASVVLLDEPTSGMDPASRRALWDLLQREKRGRSIILTTHFMDEADVLGDRVAIMANGRLQCVGTPYFLKRHYGVGYTLVVVKKEGFDYTACTDLINKYIPGIAIKEDRGPEINYSLTNIQSHVFEDMLNDFEKNVNNIKFKDYGLIATTLEDVFMSVGSDVATINSVSDDGAASLDLSGDDNLKNEFSSLEQLTKEGKVSGASLVGKHVLAVWMKLFLVWFRSWWMVLLQLAVPIVMMNATLLIVQFLISFVANIQIRHLSLEYGYSRTETLLSFNGSSSSSIGALASNAYENIFKSSGIDTMEITIVEDQSIDEYYLERASDPIEMGALRHSVLTGATFSDDVATAWFSNFAYHDVATSLASVYSALLRAFNSTAEINVYNHPIEATYKNQNDMQLLVTMISMQLSSGVASCIAIVSAVFVMFYIKERACGAKLLQKAAGIQPAVLWGSAAVFDWLLFSIICITIVITCAAFEVQGLSTFVELGRMYLCLIVYGAAMLPLNYLLSHLFEGPALGFVVIFFTNCLLGMMGPQIVEALSSPQLNTQNVADILDTIFQFFPLYSLVTCVRELNQIGLVEYSCMRGCEYISVLLPDLKECTMAVMCEHYLESCCVRESPYFEWEKPGVLRYLVVMLATCGVLWLILMTIEYRLFQKVFMFRKIPPPIPENTLDKDVADEAEHVRQISKPDLARHGLVAKNLSKYYGSNLAVDQVSFTVSDSECFGLLGVNGAGKTTTFKMLMGDENISSGEAFVSGYSVQQRLTKVHKNIGYCPQFDALFGELTGRETLRLFSLLRGLRNFSGAHADILAHSLGFLKHLDKRVDQYSGGTKRKLNTAIAFLGTTRLIFVDEPTTGVDPAAKRHVWRAMRGVQRTGRGVVLTSHSMEECEALCSRLTIMVNGRFQCLGSPQHLKNKFSQGFTLIIKLKSNEETNPSSSRNQEEAIKSYVTANFVNPKMMEEHQGLITYYLPDQTVPWSKMFGIMERAKQSLDVEDYSISQTTLEQIFLQFTKYQREGL
Domains and motifs
| Database | ID | Description | Start | End | Evalue | InterPro ID |
|---|---|---|---|---|---|---|
| PANTHER | PTHR19229 | - | 12 | 1373 | 0.0 | IPR026082 |
| Pfam | PF12698 | ABC-2 family transporter protein | 34 | 508 | 2.6e-19 | - |
| Gene3D | 3.40.50.300 | - | 557 | 797 | 3.2e-64 | - |
| CDD | cd03263 | ABC_subfamily_A | 567 | 784 | 9.0e-107 | - |
| ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. | 567 | 796 | 20.862 | IPR003439 |
| SUPERFAMILY | SSF52540 | - | 569 | 778 | 1.5e-56 | IPR027417 |
| Pfam | PF00005 | ABC transporter | 583 | 726 | 8.4e-29 | IPR003439 |
| SMART | SM00382 | - | 591 | 773 | 4.2e-07 | IPR003593 |
| ProSitePatterns | PS00211 | ABC transporters family signature. | 698 | 712 | - | IPR017871 |
| Pfam | PF12698 | ABC-2 family transporter protein | 939 | 1357 | 5.8e-24 | - |
| Gene3D | 3.40.50.300 | - | 1397 | 1640 | 3.5e-57 | - |
| PANTHER | PTHR19229 | - | 1399 | 1721 | 0.0 | IPR026082 |
| CDD | cd03263 | ABC_subfamily_A | 1408 | 1625 | 6.8e-99 | - |
| ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. | 1408 | 1637 | 17.1 | IPR003439 |
| SUPERFAMILY | SSF52540 | - | 1408 | 1629 | 3.0e-50 | IPR027417 |
| Pfam | PF00005 | ABC transporter | 1424 | 1565 | 4.4e-22 | IPR003439 |
| SMART | SM00382 | - | 1432 | 1615 | 2.8e-04 | IPR003593 |
InterPro assignment
| InterPro ID | InterPro description |
|---|---|
| IPR003439 | ABC transporter-like |
| IPR003593 | AAA+ ATPase domain |
| IPR017871 | ABC transporter, conserved site |
| IPR026082 | ABC transporter A |
| IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Gene ontology (GO) assignment
| GO category | GO ID | GO description |
|---|---|---|
| molecular function | GO:0005524 | ATP binding |
| cellular component | GO:0016021 | integral component of membrane |
| molecular function | GO:0016887 | ATPase activity |
| molecular function | GO:0042626 | ATPase-coupled transmembrane transporter activity |
| biological process | GO:0055085 | transmembrane transport |
| Species | Accession |
|---|---|
| Danaus plexippus | DPOGS200261 |
| Heliconius melpomene | HMEL005383g1.t1 |
| Manduca sexta | XP_030022234.1 |
| Plutella xylostella | g751.t1 |
| Spodoptera frugiperda (corn) | GSSPFG00014947001-PA |
| Spodoptera frugiperda (rice) | SFRICE011486-PA |
| Acyrthosiphon pisum | XP_003246127.1 XP_029344491.1 XP_029344492.1 |
| Aedes aegypti | AAEL008386-PC |
| Anopheles gambiae | AGAP006379-PA AGAP012156-PA |
| Apis mellifera | XP_397465.5 |
| Drosophila melanogaster | FBpp0304765 |
| Tribolium castaneum | XP_008199153.1 XP_015840355.1 |
| Homo sapiens | NP_001080.2 |
| Mus musculus | NP_001034670.1 NP_038883.2 XP_006524433.1 |