Position
| Chromosome | chr15 |
| Start | 12799369 |
| End | 12818071 |
| Strand | - |
view in Gbrowse: chr15:12799369..12818071
Most similar sequence in NCBI nr database
| Accession | Description | E-value | Score |
|---|---|---|---|
| XP_028039985.1 | multidrug resistance-associated protein 4-like | 0.0 | 2740 |
ORF sequence (4071 bp)
ATGGACACAGGCCCTAAGCTTAGACGACAGATGAATCCAAGATACAGAGCAAATTGGTTTTCAATTCTAACTTTTGGATGGACGTTGGAAACTTTTAAATTTGGCTACAGTCGCGACATAAAAGACAGTGATCTATATGCCCCTCTACCTGAACATCGATCACATGATCTAGGAAACTCTGTTGAAAAGGCTTGGGAAAGAGAAGTGGAGATAGCCCGAACTCGTGAAAAAAATGCTAAACCTAGTCTTTGGCTCGTTATCTTCAAGGTGTTCGGATCTGAATTTATGTTGTACGGTCTAATACTTGCCGCAATGGAATTCTTGATAAGATTACAACAACCTCTGTTTCTGGGATTGTTACTACGTTACTACAGTCCGATTCAAGACGCGAACATTGGTAATCTCACGATGAGTTCAACGTATTTATCCCGTCTTTTTAACTATTACGAGATAGATAGCAGTGTAACTTGGGGAGAGGCGGTTTTCTTTGCTTTTGGTATTGTTTTCTGTAGTACATTGAACGTTATGGTACAACACCCTATTATGATGAGTATTATGCATTTGGGCATGAAAATAAGAGTAGGCATGTGCAGCCTCATATACAGAAAAGCATTAAAAGTTAGCTTGCAAGTTATATCTGAAAACAGCGCTGGTTTGGTCGTAAATTTAATGGCAAATGATGTCAATCGATTTGATTCGGGACCGATTTTCGCACATTACCTTTGGATTGGACCTTTGGAGACGTTGTTAATGACTGTGTACCTGTATCGCGAAATGGGATTGCCCGCAATATATGGCTCGCTAGTACTCATCGTTGCCATTCCATTTCAGATATTCCTTGGATGTCAAACGGCGTATTATCGAAAAGCAACCGCAGTGACGAGCGACGAACGTGTAAATTTAATGAAAGAAATTATAATAGGTATAGAAGTGATCAAGATGTACACTTGGGAAAAACCATTCCAACGTATAATAGATATTGTTAGACGGCACGAAATTCACTACATCAAGATGACATCGTACATTCGTGGAGTGATAATGTCTTTTATAATGTTCATCTCCCGTTTTGCAATATTCTTCACTGTTTTGCTCTACGTGACGTTTGTCGGTCAAATAACCGTCGAAAATGTTTTTTTCCTAACAAGCTATTACAACATCACTAAGCAAACGATGTGTTTGTATTTCCCTCAAGCAATAGGCCAGATTGCTGAAATGAACGTGGCCGTTCAAAGAATCAGAGATTATCTTATAAGCGAGGAATGTCAAATTCAACCTAGAATTACATCTGAGGATAAATCACAAAAAGAAAGTACCAGAAAACGAGTCAGGGTTGACGAAACATTTAAACAAATTGCTGTTCAGTTTGATGAAGCTGGTACGAAATGGATAAATTCGGATAAAAAAGGAGACGTCGAAAATTTAAATTTGACTATTTATTCTGAAACAATGGCCATTGTAGTTGGATCAGTAGGTTCTGGTAAATCAACTTTATTACATTTGATTCTTAAAGAACTGCCATGCACTACAGGTAGTGTCGAAGTGAACGGAATTGTTAGCTACGCCAGTCAAAACCCATGGCTATTCGTAGGTTCCGTGAGACAAAATATTCTGTTTGGACAGCCTTATAAAAAGGCTAGATATGTGGAAGTGTGCAAGGTATGCGCTCTCGAAAGGGATATTTCTTTGTTTCCGCACGGAGATAAAACGGTCGTTGGAGAACGTGGACTATCATTAAGTGGAGGACAACGTGCCCGTATCAATTTAGCAAGAGCTGTATACAAAGAAGCAGATATTTATTTGTTGGACGATCCACTGTCGGCTGTTGATACACATGTTGCAAAGCACATTTTCGAAGAATGCATAAAAAGATTCCTGTCAAACAAAACCGTCCTCTTAGTTACGCATCAACTACAGTTCATTAAATCAATGGATCAAGTCATCATTATGGACAAAGGAAAAATAATCGCGGAAGGTGGCTTTGAGGGCTTAAGCGACAGAGAACTAAAGATACTGGAATTTATACAAGAGAACGCTAAAGAAACGCATGAAGACGAAAGCGCCCCAGCTTTACAAGGAAGCTCGATTCAACCGAGCACAATCAGTTTACACGGCAGACATTACTCTGTACTGATCGATACAAGCCTTATTGATCAAAAACCTGAGAGCGAATCACAAACAATAGGCCGAGTCAAGGGTTCGGTGTACCGTGACTATTTCCTCTCTGGGGCATCGTGTCCATGCGTTGCGATCGTCTGTGTCATGTTCTTTCTGGCACAGTTCTGTGCTAGTGCATGCGACTATTGGATCAGTCGATGGAGCGCCGTCGAGGACAGGCTTACGGGTGACGCAACCATGGATATTGCTATATGGGACGAACAGCGACTAGTCCGAAACGATTTCGTGATCATATTTGCAGTGATTACGACAGCAACTATTGTCGTCGCTTTAATAAGAGCCTTCCTGTTCTTCTCTTTGTGCATGAAATCTTCTATCCGGCTACACGACAACATGTTTGAGTCCATATCTAGATCACCGATGAACTTCTTCCACAGTAACCCGTCTGGAAGGGTATTAAATAGATTTAGTAAAGACATGGGTGCCATTGATGAATTATTACCTCAAGCAATGATAGATTGTTTTCAGATTATGTTGAATCTGGTTGGAGTTATAACTGTCATACTATTAATAGACATAGCCTTATTAATACCGATATTGTCAGCTCTGATAATATTCTATATATTGCGTGTAATTTACATTCGCACCACGGGCGCAGTGAAACGTCTAGAAGGAATAACTCGCAGTCCTGTGTTCAGTCATGTTAATGCGACCGTGTTAGGATTGGCAACGGTACGTTCGTTCGACGCTGAATTCTTATTGGCTCAGGAGTTTGATCGGCATCAAGACCTCCACAGTGGGGCCTGGTACCTCTTCATATCATGCAGCAGAGCCTTTGGATATTTCCTAGACGTCATCTGTTTGATGTTTATAATATGCGTAACCTTTAGTTGTTTGATGAAAACTGAGTTTGAAGGCAGCAGTATTGGTTTGGCCATAACCCAATGTATTTCTTTGACTGGAATTTTTCAATGGGGCATGCGGCAATCGGCCGAAATGGAAAATCAAATGACGAGCGTTGAGAGAGTACTTGAATACACGAAACTACCAAGAGAAGCTGCTCTGAAAAGCGAACCCAATAAGAAACCGCCTCCAGACTGGCCTTCACAGGGACGCATAGATTTTGAAGACCTGAGTCTCAAATATAGTCCTGACGGAAATCTTGTTTTGCACAACCTGCAATTCAGCATTCTGCCAAAAGAAAAGGTGGGAATCGTTGGAAGGACAGGTGCTGGAAAGTCTTCAATTATAGCTGCCCTATTCCGATTGGCGTATTTGGAAGGTGCAATTATAATCGACGGAATCGATATTACAAATATCGGACTGCACGATTTAAGGGAAAAAATATCGATAATTCCACAAGAGCCGGTTCTGTTTAGTGGAACAATGAGGAAAAATTTGGATCCTTTTGATGAGTATTCGGACGAGGTCTTGATAAATGCACTGAAAAGTGTAGAGTTGCAAGGCGAAGGAGAGAGCGTCGGTGTACTTTACAAAGACGTGTCTGAAGGTGGATCAAACTTCAGTGTGGGAGAACGCCAACTCGTATGTTTAGCGAGAGCCATCGTCCACAACGACCGAATTTTAGTACTGGACGAGGCGACCGCTAATGTCGATGCTCAAACAGACTCCTTGATTCAAAACACCATAAGGGAACACTTCAAAGAATGCACTGTGCTTACCATTGCGCACAGATTGAACACTGTTATAGATTCTAACAAGATTTTGGTGCTAGACGCGGGTCGTCTGGTAGAGTTCGACCATCCTCATATACTTCTGCAAAACAAGAGAGGGCAATTTCGTAAAATGGTGCAGGAAACAGGCCCGTCGATGTCGAATTTACTCCACAAACTAGCCTCTCAGAATAAAAATAGCAAGTATTCTAGAATATTTTCAGAAACAAGTGACATCTATATACAGGTCTGGTGGGGGGAATGTAATACCCCTCCAGGCTGA
Protein sequence (1356 aa)
MDTGPKLRRQMNPRYRANWFSILTFGWTLETFKFGYSRDIKDSDLYAPLPEHRSHDLGNSVEKAWEREVEIARTREKNAKPSLWLVIFKVFGSEFMLYGLILAAMEFLIRLQQPLFLGLLLRYYSPIQDANIGNLTMSSTYLSRLFNYYEIDSSVTWGEAVFFAFGIVFCSTLNVMVQHPIMMSIMHLGMKIRVGMCSLIYRKALKVSLQVISENSAGLVVNLMANDVNRFDSGPIFAHYLWIGPLETLLMTVYLYREMGLPAIYGSLVLIVAIPFQIFLGCQTAYYRKATAVTSDERVNLMKEIIIGIEVIKMYTWEKPFQRIIDIVRRHEIHYIKMTSYIRGVIMSFIMFISRFAIFFTVLLYVTFVGQITVENVFFLTSYYNITKQTMCLYFPQAIGQIAEMNVAVQRIRDYLISEECQIQPRITSEDKSQKESTRKRVRVDETFKQIAVQFDEAGTKWINSDKKGDVENLNLTIYSETMAIVVGSVGSGKSTLLHLILKELPCTTGSVEVNGIVSYASQNPWLFVGSVRQNILFGQPYKKARYVEVCKVCALERDISLFPHGDKTVVGERGLSLSGGQRARINLARAVYKEADIYLLDDPLSAVDTHVAKHIFEECIKRFLSNKTVLLVTHQLQFIKSMDQVIIMDKGKIIAEGGFEGLSDRELKILEFIQENAKETHEDESAPALQGSSIQPSTISLHGRHYSVLIDTSLIDQKPESESQTIGRVKGSVYRDYFLSGASCPCVAIVCVMFFLAQFCASACDYWISRWSAVEDRLTGDATMDIAIWDEQRLVRNDFVIIFAVITTATIVVALIRAFLFFSLCMKSSIRLHDNMFESISRSPMNFFHSNPSGRVLNRFSKDMGAIDELLPQAMIDCFQIMLNLVGVITVILLIDIALLIPILSALIIFYILRVIYIRTTGAVKRLEGITRSPVFSHVNATVLGLATVRSFDAEFLLAQEFDRHQDLHSGAWYLFISCSRAFGYFLDVICLMFIICVTFSCLMKTEFEGSSIGLAITQCISLTGIFQWGMRQSAEMENQMTSVERVLEYTKLPREAALKSEPNKKPPPDWPSQGRIDFEDLSLKYSPDGNLVLHNLQFSILPKEKVGIVGRTGAGKSSIIAALFRLAYLEGAIIIDGIDITNIGLHDLREKISIIPQEPVLFSGTMRKNLDPFDEYSDEVLINALKSVELQGEGESVGVLYKDVSEGGSNFSVGERQLVCLARAIVHNDRILVLDEATANVDAQTDSLIQNTIREHFKECTVLTIAHRLNTVIDSNKILVLDAGRLVEFDHPHILLQNKRGQFRKMVQETGPSMSNLLHKLASQNKNSKYSRIFSETSDIYIQVWWGECNTPPG
Domains and motifs
| Database | ID | Description | Start | End | Evalue | InterPro ID |
|---|---|---|---|---|---|---|
| PANTHER | PTHR24223 | - | 6 | 1329 | 0.0 | - |
| PANTHER | PTHR24223:SF324 | - | 6 | 1329 | 0.0 | - |
| Gene3D | 1.20.1560.10 | - | 91 | 419 | 4.5e-09 | IPR036640 |
| SUPERFAMILY | SSF90123 | - | 96 | 416 | 3.5e-23 | IPR036640 |
| Pfam | PF00664 | ABC transporter transmembrane region | 97 | 387 | 2.6e-18 | IPR011527 |
| CDD | cd18593 | ABC_6TM_MRP4_D1_like | 99 | 412 | 4.8e-89 | - |
| ProSiteProfiles | PS50929 | ABC transporter integral membrane type-1 fused domain profile. | 99 | 383 | 24.808 | IPR011527 |
| Gene3D | 3.40.50.300 | - | 421 | 694 | 2.0e-73 | - |
| ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. | 442 | 676 | 21.722 | IPR003439 |
| SUPERFAMILY | SSF52540 | - | 453 | 666 | 4.5e-54 | IPR027417 |
| CDD | cd03250 | ABCC_MRP_domain1 | 472 | 653 | 4.4e-94 | - |
| Pfam | PF00005 | ABC transporter | 472 | 605 | 1.7e-18 | IPR003439 |
| SMART | SM00382 | - | 480 | 660 | 6.6e-10 | IPR003593 |
| ProSitePatterns | PS00211 | ABC transporters family signature. | 578 | 592 | - | IPR017871 |
| Gene3D | 1.20.1560.10 | - | 745 | 1059 | 2.4e-35 | IPR036640 |
| CDD | cd18601 | ABC_6TM_MRP4_D2_like | 746 | 1052 | 7.4e-105 | - |
| Pfam | PF00664 | ABC transporter transmembrane region | 749 | 1017 | 8.9e-31 | IPR011527 |
| ProSiteProfiles | PS50929 | ABC transporter integral membrane type-1 fused domain profile. | 785 | 1040 | 29.645 | IPR011527 |
| SUPERFAMILY | SSF90123 | - | 788 | 1057 | 4.8e-48 | IPR036640 |
| Gene3D | 3.40.50.300 | - | 1061 | 1312 | 3.5e-79 | - |
| SUPERFAMILY | SSF52540 | - | 1067 | 1309 | 2.9e-63 | IPR027417 |
| CDD | cd03244 | ABCC_MRP_domain2 | 1076 | 1294 | 4.5e-109 | - |
| ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. | 1078 | 1310 | 15.28 | IPR003439 |
| Pfam | PF00005 | ABC transporter | 1095 | 1241 | 1.6e-29 | IPR003439 |
| SMART | SM00382 | - | 1104 | 1287 | 3.3e-11 | IPR003593 |
| ProSitePatterns | PS00211 | ABC transporters family signature. | 1213 | 1227 | - | IPR017871 |
InterPro assignment
| InterPro ID | InterPro description |
|---|---|
| IPR003439 | ABC transporter-like |
| IPR003593 | AAA+ ATPase domain |
| IPR011527 | ABC transporter type 1, transmembrane domain |
| IPR017871 | ABC transporter, conserved site |
| IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| IPR036640 | ABC transporter type 1, transmembrane domain superfamily |
Gene ontology (GO) assignment
| GO category | GO ID | GO description |
|---|---|---|
| molecular function | GO:0005524 | ATP binding |
| cellular component | GO:0016021 | integral component of membrane |
| molecular function | GO:0016887 | ATPase activity |
| molecular function | GO:0042626 | ATPase-coupled transmembrane transporter activity |
| biological process | GO:0055085 | transmembrane transport |
| Species | Accession |
|---|---|
| Danaus plexippus | DPOGS208713 |
| Heliconius melpomene | HMEL015261g1.t1 |
| Manduca sexta | XP_030029722.1 |
| Plutella xylostella | g27790.t1 |
| Spodoptera frugiperda (corn) | GSSPFG00034035001.4-PA |
| Spodoptera frugiperda (rice) | SFRICE011351-PA |
| Acyrthosiphon pisum | XP_029346478.1 |
| Aedes aegypti | AAEL018267-PB AAEL018267-PC AAEL018267-PD AAEL018267-PE AAEL018267-PF AAEL018267-PG |
| Anopheles gambiae | AGAP006427-PA |
| Apis mellifera | XP_393750.5 |
| Drosophila melanogaster | FBpp0079228 FBpp0297935 |
| Tribolium castaneum | XP_015835265.1 |
| Homo sapiens | NP_001288758.1 NP_005836.2 |
| Mus musculus | NP_001028508.2 |