Position
| Chromosome | chr15 |
| Start | 9060862 |
| End | 9114315 |
| Strand | + |
view in Gbrowse: chr15:9060862..9114315
Most similar sequence in NCBI nr database
| Accession | Description | E-value | Score |
|---|---|---|---|
| XP_028037143.1 | multidrug resistance-associated protein 4-like isoform X1 | 0.0 | 2879 |
ORF sequence (4188 bp)
ATGGTCAGTGGAAATAAAGACGCGAACGATCCCACGAAGATACCGCCGAAGAATCGTGAAAAGAAATCTAATAATTACAAGAGAGCGAACTTCCTCTCGAAGGCATGGTTCGTCTGGATGATGCCGACTTTCTGGCGTGGCTACAAACGAGATCTCTACGATTCTGATCTCACGAAGCCTAAAGAAAACCATCATTCCGACAAGCTTGGTGATCGGCTTGAAAAAAAATGGTTGGAGGAAATAGCTTTGGCAAACAAGATTGGTCGAAAGCCTTCCCTACTCCGCGCGATGACGAAAACCTTCTGGATGAGCTACGCGCCCTCTGGTCTTATGTTTCTAGTACAGGCACTATTATTTAAGCCATTCCAGCCTGTCGTTTTGAGTATGATGCTCGCCTATTGGGAACCAGGGTCCGACATGACATATGAGCAAGCGGTGTACTGCGCCACCACTGTGATACTGATGTCTTTGATAATCGCCTTCCTGAATCACCACGGTTCGTACTCCACACAACAATTTGGAATGAAAGTGCGCATCGCTGCCTGCTCTCTCATTTACAGAAAAGTGATGCGAATGAGTTCCAGTGCTTTGGCTCAAACAACAGCCGGTCAAGTAGTCAATCTACTGTCCAATGATGTGAACAGATTCGACTACGCATTCATCTACACACATTTTATTTGGCTCCTGCCTCTCCAAGTGATAGTGGTCTGCTACCTCATCTACATCAAAATCGGATATGCGGCTGTCGTCGGTGTCATCGGCATCGTGTTGCAAACAATACCCGTTCAATCGTACATGAGTAAACTGGCGGCGAGGCTGCGCATGAAAACAGCATGCAAAACAGATGAACGTGTCAGAATTATGGACGAAATCATTAGTGGTATGCAGGTTATTAAAATGTACGCTTGGGAGAAGCCTTTCGAGCAAGTTGTAGCCCTGGCTCGGAAGAACGAAATCAACTGCATCACGTCAGCGTCTTACCTCCGAGGAGTGTACCTGAGCTTCATGGTGTTCACGGAACGACTCACGCTATATATCACATTACTTTCGCACTCTTTATTCGGTTATCAAGTCACCGCTGATATTGTATTCCCGTTGGCGCAATTCTACAACACACTACAAGGGACTCTGTCGATAATCATGTCTAACGCCGTATCGTTTTTGGCTGAGGCTTTGATCTCGATACAACGCCTCGAAGCGTTCTTGCTGTTTGATGAGAGAGAGGATTTACGTAGTGTCCCTGATGTGGACATTGCTAAGCTAGTACAGAGCATTGACCATCAAAAAAAAAAGAAACTTAGTGAAGTGGAAAAAACTACTAGTACTTTTAAGAAAATCGATGAAGAAGATTATTTCAATCTGGGATTTGAATGCACAGAAAAGGGTTTGACGATAATTTCTCAACCTCCTCGTGATCCCCCCGTAAGTCCTGATATCGGAATCTTAATACAAGACGTGTCTGCCAATTGGACGGAGACTGGCCCTCTCACATTATGTAACGTTAACATCACAGTACCGAAAGGAAAACTCTGCGCTATAATCGGATCTGTGGGCTCTGGGAAGAGTTCCATATTACAGTTACTTTTAAATGAACTACGCCCTATAAGTGGACGTGTTTATCACTCCGGCCCACTGTCATATGCAAGTCAGGAGCCTTGGCTTTTCGTGGCGACGGTCAGACAGAACATTCTATTTGGCCTACCGTACAACCCCAAAAAATACAAAGAGGTTATTAGAGTGTGTGCCCTTCAAAAAGACTTTCAACAGTTTCCACACGGAGATCAAACCTTAGTAGGTGAACGAGGCGCGTCCCTTTCTGGAGGACAAAGGGCTCGTATCAACCTCGCTAGAGCTGTTTATAGACAAGCGGAACTGTATCTCTTGGATGATCCTTTATCGGCGGTGGACGCTCATGTCGGTCGGCAATTGTTCGATGAGTGCATCAGCGGATACCTCCGGCACACAACTCGAGTGCTTGTCACACATCAACTACACTACCTCAAGGCTGCCGATTATATAATCATCATGAATAATGGTACGGTAGACGCTTGTGGAACATACGAAGAACTAATGACTTCCGGTAAAGACTTCGCCAAACTTTTAACCTCTTTGCAAGACGAGAATGAAGATGAACCTAAAAAACTACCTTTGCCAATGTCCAGGCGAACATCAGCCCGGTTATCAACAACACGTCGACCTTCGATGTCGGAGTCAATGACTGGTTGCGAAGGTCCTGCACAAGAGATGGAGGAGGAAGAAAGAGAATCAGGCTCGATGGGCTGGCACGTTTACAAAGCATATCTGACGGCTGGCGGAGGAAGTACTCGGCTGATGTTTACTGTTCTTATACTCGTAATAGGACAACTATCGGCCACGCTTTGTGACTATTGGGTTACATTCTGGACTAACGAAGTTACAAGAATGAAAGAAAAAGAAAGCAATAATACCACAAAGGACTATGAACTAATGCTGACACCGAAAAACAATACCTTTAGTGTTACCAACTACTTCTCCGGAACTGAAGCCCAACCAGATCTAAACATCCACGCATTCATCGGTCCTCTGGATACGGCGCAGTATCTCTACGTTTACACAGCACTGATCATTTGCTGTATCTTCTTCATAACGGCCCGAGCGTTTATGTTCTTCAAAGTTTGCATGACGTCCTCCAGGAACCTCCACAACGACATGTTTCACTCGATGCTTAGAGGCGTAATGCGATTCTTCGATTCCAATTCTTCTGGTAGGCGTGACAGTCTCTCATTCGCAAAAAATATTGGAGCTTTGGACGAGCTCTTGCCGCGTTTCTTGCTGGAGTGCATACAAATATATTTGGTGATGTTCAGCATCCTGGCGTTGAATGCAGCGGCTTTAATATGGACTTTACTGCCCACCACAATCATATTGCTCCTATTTTACACGATACTGCAAATATACCTAAAATCTGCACAGTCTATCAAACGATTGGAAGGCACAACACGAAGCCCGGTGTTTTCTCACATGTCGGCCACTCTCAACGGCATGAGCACAATCCGTTCTGCAGGAGCACAACAAAGATTGATTCAGGAATTTGATAATTTCCAAGATATACACACGTCAACATGGAGCAGCTATTTAGCAAGTGGCGTCACCCTTGGCTTTTGGCTCGATTTAATCTGCGTGCTGTATCTGGCGATCGTCATTATAGCCTTCCTCGTGATAGACAGCAAGACAATATTTTCCGGAAATGTGGGTCTAGCGATTTCGCAAACGCTAATCTTGACAGGAATGTTGCAATTCGGTGTAAGACAAACAGCTGAAGTCATCTCGCAAATGACAAGTGTCGAAAGGATATTGCAGTACACACACATCGAAAGGGAAAGTCAGTGGGAAAAAGGAGAACGCGAAACTCCGAAAGGCTGGCCGTCGAATGGTCGTATTGAGTTCCGTAACTGCTTCATGAAGTACACACCTCAAGACCTGCCCGTACTGAAGAATCTCAATTTAGTCATTGAAAGTGGATGGAAGGTCGGCATCGTGGGTAGAACGGGTGCCGGAAAATCTTCTCTGATATCCTCCTTGTTTCGACTTGCGATAGTTGAAGGAGAGATTCTCATTGATGACATCGAGACCGGATATTTGGCTCTACAGGATCTTCGTTCGAAGATATCGATAATCCCTCAAGAGCCGGTATTGTTCTCGGCCACCGTACGATACAATTTGGATCCCTTCAATAACTACAAGGACGAGGAATTGTGGAAAGCTTTGGAAGCTGTTGATCTAAAGGCCGCTGTTCCTTCTTTAGATTTCAAGGTATCCGAAGGTGGATCTAACTTCTCTCTTGGACAAAGGCAATTGGTTTGTCTCGCGCGTGCTATCTTACGAGGAAATCGTATTCTGGTTCTGGACGAAGCCACCGCTAATGTTGATCCCAAAACTGACGAATTTATTCAAAGAACGATACGGACACGATTTGCTGATTGCACCGTGCTGACTGTAGCGCATCGTCTTAACACCATCATGGACTCCGATAGAGTAATGGTGATGGATGCCGGACGGCTTGTGGAGTTCGATCATCCCTACAAACTGCTCAGTAATCCCGACGGCTATTTCGCGAAAATGGTTAAAGAAACAAATGAAAAAATGTCCCAACAATTATATGAAATAGCGAAAGATACGTACATAAAAAACGGAGGTAGAATTGAGTAA
Protein sequence (1395 aa)
MVSGNKDANDPTKIPPKNREKKSNNYKRANFLSKAWFVWMMPTFWRGYKRDLYDSDLTKPKENHHSDKLGDRLEKKWLEEIALANKIGRKPSLLRAMTKTFWMSYAPSGLMFLVQALLFKPFQPVVLSMMLAYWEPGSDMTYEQAVYCATTVILMSLIIAFLNHHGSYSTQQFGMKVRIAACSLIYRKVMRMSSSALAQTTAGQVVNLLSNDVNRFDYAFIYTHFIWLLPLQVIVVCYLIYIKIGYAAVVGVIGIVLQTIPVQSYMSKLAARLRMKTACKTDERVRIMDEIISGMQVIKMYAWEKPFEQVVALARKNEINCITSASYLRGVYLSFMVFTERLTLYITLLSHSLFGYQVTADIVFPLAQFYNTLQGTLSIIMSNAVSFLAEALISIQRLEAFLLFDEREDLRSVPDVDIAKLVQSIDHQKKKKLSEVEKTTSTFKKIDEEDYFNLGFECTEKGLTIISQPPRDPPVSPDIGILIQDVSANWTETGPLTLCNVNITVPKGKLCAIIGSVGSGKSSILQLLLNELRPISGRVYHSGPLSYASQEPWLFVATVRQNILFGLPYNPKKYKEVIRVCALQKDFQQFPHGDQTLVGERGASLSGGQRARINLARAVYRQAELYLLDDPLSAVDAHVGRQLFDECISGYLRHTTRVLVTHQLHYLKAADYIIIMNNGTVDACGTYEELMTSGKDFAKLLTSLQDENEDEPKKLPLPMSRRTSARLSTTRRPSMSESMTGCEGPAQEMEEEERESGSMGWHVYKAYLTAGGGSTRLMFTVLILVIGQLSATLCDYWVTFWTNEVTRMKEKESNNTTKDYELMLTPKNNTFSVTNYFSGTEAQPDLNIHAFIGPLDTAQYLYVYTALIICCIFFITARAFMFFKVCMTSSRNLHNDMFHSMLRGVMRFFDSNSSGRRDSLSFAKNIGALDELLPRFLLECIQIYLVMFSILALNAAALIWTLLPTTIILLLFYTILQIYLKSAQSIKRLEGTTRSPVFSHMSATLNGMSTIRSAGAQQRLIQEFDNFQDIHTSTWSSYLASGVTLGFWLDLICVLYLAIVIIAFLVIDSKTIFSGNVGLAISQTLILTGMLQFGVRQTAEVISQMTSVERILQYTHIERESQWEKGERETPKGWPSNGRIEFRNCFMKYTPQDLPVLKNLNLVIESGWKVGIVGRTGAGKSSLISSLFRLAIVEGEILIDDIETGYLALQDLRSKISIIPQEPVLFSATVRYNLDPFNNYKDEELWKALEAVDLKAAVPSLDFKVSEGGSNFSLGQRQLVCLARAILRGNRILVLDEATANVDPKTDEFIQRTIRTRFADCTVLTVAHRLNTIMDSDRVMVMDAGRLVEFDHPYKLLSNPDGYFAKMVKETNEKMSQQLYEIAKDTYIKNGGRIE
Domains and motifs
| Database | ID | Description | Start | End | Evalue | InterPro ID |
|---|---|---|---|---|---|---|
| PANTHER | PTHR24223 | - | 19 | 134 | 0.0 | - |
| PANTHER | PTHR24223:SF334 | - | 19 | 134 | 0.0 | - |
| Gene3D | 1.20.1560.10 | - | 85 | 403 | 2.1e-12 | IPR036640 |
| SUPERFAMILY | SSF90123 | - | 94 | 398 | 1.7e-28 | IPR036640 |
| CDD | cd18579 | ABC_6TM_ABCC_D1 | 108 | 398 | 3.9e-97 | - |
| Pfam | PF00664 | ABC transporter transmembrane region | 111 | 377 | 1.6e-26 | IPR011527 |
| ProSiteProfiles | PS50929 | ABC transporter integral membrane type-1 fused domain profile. | 118 | 389 | 26.911 | IPR011527 |
| PANTHER | PTHR24223 | - | 144 | 442 | 0.0 | - |
| PANTHER | PTHR24223:SF334 | - | 144 | 442 | 0.0 | - |
| SUPERFAMILY | SSF52540 | - | 474 | 702 | 2.1e-58 | IPR027417 |
| Gene3D | 3.40.50.300 | - | 475 | 722 | 1.1e-74 | - |
| PANTHER | PTHR24223 | - | 479 | 1389 | 0.0 | - |
| PANTHER | PTHR24223:SF334 | - | 479 | 1389 | 0.0 | - |
| CDD | cd03250 | ABCC_MRP_domain1 | 481 | 680 | 1.1e-109 | - |
| ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. | 481 | 703 | 24.25 | IPR003439 |
| Pfam | PF00005 | ABC transporter | 499 | 632 | 8.8e-20 | IPR003439 |
| SMART | SM00382 | - | 507 | 680 | 4.2e-10 | IPR003593 |
| ProSitePatterns | PS00211 | ABC transporters family signature. | 605 | 619 | - | IPR017871 |
| CDD | cd18601 | ABC_6TM_MRP4_D2_like | 777 | 1115 | 8.2e-86 | - |
| Pfam | PF00664 | ABC transporter transmembrane region | 784 | 1089 | 3.8e-21 | IPR011527 |
| ProSiteProfiles | PS50929 | ABC transporter integral membrane type-1 fused domain profile. | 833 | 1103 | 22.269 | IPR011527 |
| Gene3D | 1.20.1560.10 | - | 843 | 1122 | 4.0e-24 | IPR036640 |
| SUPERFAMILY | SSF90123 | - | 856 | 1120 | 1.2e-35 | IPR036640 |
| Gene3D | 3.40.50.300 | - | 1123 | 1372 | 2.8e-80 | - |
| SUPERFAMILY | SSF52540 | - | 1131 | 1368 | 3.5e-66 | IPR027417 |
| CDD | cd03244 | ABCC_MRP_domain2 | 1138 | 1353 | 1.2e-121 | - |
| ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. | 1140 | 1369 | 17.247 | IPR003439 |
| Pfam | PF00005 | ABC transporter | 1157 | 1300 | 5.9e-29 | IPR003439 |
| SMART | SM00382 | - | 1166 | 1346 | 1.1e-08 | IPR003593 |
| ProSitePatterns | PS00211 | ABC transporters family signature. | 1272 | 1286 | - | IPR017871 |
InterPro assignment
| InterPro ID | InterPro description |
|---|---|
| IPR003439 | ABC transporter-like |
| IPR003593 | AAA+ ATPase domain |
| IPR011527 | ABC transporter type 1, transmembrane domain |
| IPR017871 | ABC transporter, conserved site |
| IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| IPR036640 | ABC transporter type 1, transmembrane domain superfamily |
Gene ontology (GO) assignment
| GO category | GO ID | GO description |
|---|---|---|
| molecular function | GO:0005524 | ATP binding |
| cellular component | GO:0016021 | integral component of membrane |
| molecular function | GO:0016887 | ATPase activity |
| molecular function | GO:0042626 | ATPase-coupled transmembrane transporter activity |
| biological process | GO:0055085 | transmembrane transport |
| Species | Accession |
|---|---|
| Danaus plexippus | DPOGS208066 |
| Heliconius melpomene | HMEL003351g1.t2 |
| Manduca sexta | XP_030034568.1 |
| Plutella xylostella | g34638.t1 |
| Spodoptera frugiperda (corn) | GSSPFG00031184001.2-PA |
| Spodoptera frugiperda (rice) | SFRICE001146-PA |
| Acyrthosiphon pisum | XP_016655768.1 XP_016655769.1 XP_029345670.1 XP_029345671.1 |
| Aedes aegypti | AAEL018267-PB AAEL018267-PC AAEL018267-PD AAEL018267-PE AAEL018267-PF AAEL018267-PG |
| Anopheles gambiae | AGAP003221-PA |
| Apis mellifera | XP_006563569.1 |
| Drosophila melanogaster | FBpp0088845 FBpp0297167 |
| Tribolium castaneum | XP_969849.1 |
| Homo sapiens | NP_001337447.1 |
| Mus musculus | NP_001028508.2 |