Position
| Chromosome | chr14 |
| Start | 2533174 |
| End | 2580163 |
| Strand | - |
view in Gbrowse: chr14:2533174..2580163
Most similar sequence in NCBI nr database
| Accession | Description | E-value | Score |
|---|---|---|---|
| XP_021208843.1 | multidrug resistance protein homolog 49 | 0.0 | 2719 |
ORF sequence (4137 bp)
ATGCCTATTACAATTGAGGATTGGAAGTCTTCATGGTATTTGCGTTATGGTATCAATGGATCGACCGTCTCACGAAGACCCGGCGGAGCTGGTAACAATGTACACGATATAAGATGCGAGCAAAACATTCTATCGGTTAGCCTGAGAATGAAACGCGATGAGTCCTCAAAGAGCGTAACCAACTTCCAGCAGCGACGTCTCAGCGAGCAGCGGCCGGCGTTCACGTACGGCTGGCGATCCAACTCGCTTACCATCCAAACACTAGCTCAGCATTCCGCTTATCTAGCTGAGAAAGCGCTCAACAAGCAGGCTGAAGAAGAGTTATTACAAAGCACACCGGTTTCGTGGTTACGATTATATAGATACGCAAAATTATGGGAGATCTTGCTACTCATCACGGGTGTGATCCTGGCCAGCTTGAATGGGTTGTTCGTGCCAATAGGAGTTATCATATATGGAGAGTTTACGTCGCTACTGATCGACAGAACTGTGATGGTCGGCACCTCCGGGAAGACTCTAACCATTGCGATGTTCGGTGGTGGACGAATATTGACGAACGCCAGCCGAGAAGAGAATAGGTTGGCATTAATCGAAGACTCGCAAGCGTTCGGTGTTGGATGCACGGTGTTCTCCATAGCTCAGTTCATAATTGGTGCCATAAGTGTGGACCTATTCAACGTTACAGCGTTGAGACAGATTGAAAGGGTAAAAACGCATTTCCTACAAGCGGTCCTCCGACAGGACCTGACCTGGTACGACTTGAACACCTCAATGAATTTCGCCACCAAGGTCTCTGATGACTTGGAGAAGTTTCGCGAGGGTATAGGTGAGAAAGTCCCCATGCTCATCTATCTGGTGATGTCCTTTGTGACCGCTGTCATTATCTCGTTCGTGTATGGCTGGGAGCTCACGCTGGTCATTCTGTCTTGTACCCCGGTGGTGATCGCAACAACCGCTATAGTTGCAAAGGTGCAGTCATCGCTGACGACGCAAGAGCTGAAAGCCTATAGTGTGGCTGGTATCGTGGCTGAAGAGGTTCTGTCTTCAATCAGAACTGTCGTTGCTTTCGGAGGCGAAGAGAAAGAAATTAAAAGGTACAGCGTCCGCTTGGAGCCGGCGAACAAGATGGGGACACGTAAAGGAATATTTTCGGGCTTCGGAAGCGGGGTCATGTGGCTCATTATATACGGGACATACGCGCTGTCCTTCTGGTACGGAGTCGGCCTCATCCTGAAGTCTCGCCACCAGGAAACGCCTGTGTACACTCCAGCTGTGTTGATGATTATTTTCTTCAGTGTACTCCAAGGGGCTCAGAACGTTGGTCTTACCGCTCCTCATTTAGAGGCCATAGCGAACGCGCGAGCTTCTGCGGCCTCCGTCTATGCCGTCATCGATAGGAAACCGACTATTGACAGTCTCTCCACGGAAGGCGCCAAACCAGAGTTCAAGGGAGACCTGGAACTGGAAGACGTGGTCTTTAGATATCCGGCGAGAGCGGATGTGCAGGTTCTCAATGGATTAAATCTGAAAATAAACGAGAACGAAACGATAGCGCTGGTGGGTCCGAGCGGCTGCGGTAAGTCCACGGTCCTGCAGCTCTTACAGAGGATGTACGACCCCGACCAGGGCTCCGTGAGGGCCAGCGGCCATGACTTGCGGACCATGAACGTGAGGCACCTCAGAAATCACATCGCTGTCGTCGGCCAAGAACCAGTGCTGTTCGCGGGGACCATCAAAGAGAATATCCGAATGAGCAATCCATCTTGCACTGATGATGAGGTCATCGTAGCCGCTAAACAAGCTTACTGCCATGATTTCATAAGGAAATTGCCGGATGGCTACGACACGCCCATAGGCGAGCGCGGCGCCCAGCTCTCCGGCGGACAGAAGCAGCGCATCGCCATAGCTCGCGCGCTGGTGCGGCGCCCCAAGCTGCTGCTGCTGGACGAGGCCACGTCGGCGCTGGACTCGCACAGCGAGGCCAAGGTGCAGCGCGCGCTGGACGCCGCCGCGCACGGACGCACCACCGTCATGGTCTCGCACAGATTGGTGACCGTACTGAACGCGTCTCGCATAGTCTTCATAGACAAGGGAGAAGTAATCGAGGAAGGCACTCACGAGGAGTTGATGTCGCTGCGCGGTCGGTACTACCAGCTGGTGCTGGAGAATGAGCCCAGTATGGCGCCAGGGGCCGCCTCAAGCAACGACATGCAGAAACATGCGAGAATCCGGAAGCCCAAACTACAAAAATTGGCTTCCGTCGACTCGATCAAGAGCAATTTTACCCAAGACGACTCCGGCTCGGAGGACAGTGTGATGCTGGATGAGCCCAAAGAGGAGGAGATCAAACCGACGACTTGGGACATAATGAAACTGTGCGAGCCGGAGAAGTGGCTGATGATCGTCGGTGTCCTAGCCGCCTTCTCTGTAGGCTCCTCCTTCCCGATGTTCGCGATCTTGTTCGGCGAAACTTACGGGTTATTGGAGAATCGTAACGACGAGTGGGTCCGGGGCGAGACCAACATGATAGCGGTCCTGTTCATATTGGTGGGCGTCTTAACCGGAGTGGGGATATTCTTCCAAATTTACATCTTCAATTTAACTGGAGTCAGGCTGACGGCTAGGCTAAGGGTGGCGGTATTCCGTAAGATGTTAGCTCAGGAGATCGGCTGGTTCGACGATCCAAAGAACGGAGTCGGAGCGCTCTGCGCCAGGCTAGCCGCTGATGCTGCAGCAGTACAAGGCGCAACTGGCACACGGATAGGCGCATTAATGCAAGCCACAGCTACAATCGTGATAGGGATCGCCCTCTCGCTGTACTACACGTGGCAGATGACGCTAGTGTCCTTGGTCTCAGTCCCTATGGTCATTGGAGCGGTCGTGCTGGAAGGGCGGGTGCTGTCTGAAGGAATAGCCGAGGTCAGGGAGGCCTCCGACCGTGCTACAACCATAGCCACGGAGGCCATCACGAACATCAGGACGGTCTCTGCTTTCTGCGGCGAGGAGGGGGCGCTGCGGCGGTACGAGGAGGCGGGGGGCGCGGCGCAACGCACTGCGCGGCGCTCGCTGCGGTGGCGCGGCGCCGTGTTCTCGTTCGGGCAGACGGCGCCCGTGGCCGGGTACGCACTGGCGCTCTGGTACGGCGGCGTGCTCGTCGCCAACCGGGAGCTGCACTACAAGTCCGTCATCAAGGTATCGGAGGCGCTAGTGTTCGGCGCGTGGATGATGGGGCAGGCGCTCGCGTTCGCCCCGAACTTCGGCGCGGCGATGAGCGCGGCCGGCCGCGTCATGACGCTGCTGCAGCGGCGGGCGCTCGTCGAGGACACGCACGCGCCCGCCCTGCACGAAAACTACGTGGCAGAAGGCAAGATCCAGTACAAGAACATAAAGTTCCGGTACCCGACGCGGCGCGAGGTGGAGGTGCTGGCCGGCCTGAGCCTCGCGATCCCGCGCGGGGTGCGCGCCGCGCTCGTGGGGCCCAGCGGCTGCGGCAAGTCCACGCTCATACAGCTGCTGCAGCGGCTCTACGACCCGGACGACGGGAACGTATACCTGGACGACTACAGCATTACATCGGACATGCGCTTGTCGACGCTGCGGCGGAACCTGGGCATAGTCTCCCAGGAGCCGGTGCTATTCGACCGGACCATCGCCGACAACATCGCGTACGGCGACAACACCAGAGACGTGCCCATCGAGGAAATTGTCAAAGCGGCTAAAGAGGCGAACGTTCATACCTTTATATCCGCTCTGCCGAATGGCTACGACACGCGACTGGGGGCTCGCGCGTCGCAGCTGTCGGGGGGACAGAAGCAGCGCATCGCCATCGCGCGAGCGCTCGTGCGGAACCCGCGCGTGTTACTGCTCGACGAGGCGACATCAGCACTCGACACTCACAGCGAAAAGGTGGTCCAAGAAGCACTGGACAAGGCCAGCGAAGGCCGCACGTGCCTCATCATAGCTCACCGTCTGTCGACGATACAGAACGCGGATATTATCTGCGTCATCGATAAAGGGGTGGTCGCCGAAACCGGGACGCATCGCGAACTGATCAAGAGAAAGGGAATTTACGCCAAGCTGTACGAGCTGCAGTGCGGCTTCGTCGAGGAAAGCGAAGAGAATCTGCATAACGAATAG
Protein sequence (1378 aa)
MPITIEDWKSSWYLRYGINGSTVSRRPGGAGNNVHDIRCEQNILSVSLRMKRDESSKSVTNFQQRRLSEQRPAFTYGWRSNSLTIQTLAQHSAYLAEKALNKQAEEELLQSTPVSWLRLYRYAKLWEILLLITGVILASLNGLFVPIGVIIYGEFTSLLIDRTVMVGTSGKTLTIAMFGGGRILTNASREENRLALIEDSQAFGVGCTVFSIAQFIIGAISVDLFNVTALRQIERVKTHFLQAVLRQDLTWYDLNTSMNFATKVSDDLEKFREGIGEKVPMLIYLVMSFVTAVIISFVYGWELTLVILSCTPVVIATTAIVAKVQSSLTTQELKAYSVAGIVAEEVLSSIRTVVAFGGEEKEIKRYSVRLEPANKMGTRKGIFSGFGSGVMWLIIYGTYALSFWYGVGLILKSRHQETPVYTPAVLMIIFFSVLQGAQNVGLTAPHLEAIANARASAASVYAVIDRKPTIDSLSTEGAKPEFKGDLELEDVVFRYPARADVQVLNGLNLKINENETIALVGPSGCGKSTVLQLLQRMYDPDQGSVRASGHDLRTMNVRHLRNHIAVVGQEPVLFAGTIKENIRMSNPSCTDDEVIVAAKQAYCHDFIRKLPDGYDTPIGERGAQLSGGQKQRIAIARALVRRPKLLLLDEATSALDSHSEAKVQRALDAAAHGRTTVMVSHRLVTVLNASRIVFIDKGEVIEEGTHEELMSLRGRYYQLVLENEPSMAPGAASSNDMQKHARIRKPKLQKLASVDSIKSNFTQDDSGSEDSVMLDEPKEEEIKPTTWDIMKLCEPEKWLMIVGVLAAFSVGSSFPMFAILFGETYGLLENRNDEWVRGETNMIAVLFILVGVLTGVGIFFQIYIFNLTGVRLTARLRVAVFRKMLAQEIGWFDDPKNGVGALCARLAADAAAVQGATGTRIGALMQATATIVIGIALSLYYTWQMTLVSLVSVPMVIGAVVLEGRVLSEGIAEVREASDRATTIATEAITNIRTVSAFCGEEGALRRYEEAGGAAQRTARRSLRWRGAVFSFGQTAPVAGYALALWYGGVLVANRELHYKSVIKVSEALVFGAWMMGQALAFAPNFGAAMSAAGRVMTLLQRRALVEDTHAPALHENYVAEGKIQYKNIKFRYPTRREVEVLAGLSLAIPRGVRAALVGPSGCGKSTLIQLLQRLYDPDDGNVYLDDYSITSDMRLSTLRRNLGIVSQEPVLFDRTIADNIAYGDNTRDVPIEEIVKAAKEANVHTFISALPNGYDTRLGARASQLSGGQKQRIAIARALVRNPRVLLLDEATSALDTHSEKVVQEALDKASEGRTCLIIAHRLSTIQNADIICVIDKGVVAETGTHRELIKRKGIYAKLYELQCGFVEESEENLHNE
Domains and motifs
| Database | ID | Description | Start | End | Evalue | InterPro ID |
|---|---|---|---|---|---|---|
| PANTHER | PTHR24221 | - | 111 | 1364 | 0.0 | IPR039421 |
| PANTHER | PTHR24221:SF410 | - | 111 | 1364 | 0.0 | - |
| SUPERFAMILY | SSF90123 | - | 118 | 471 | 3.3e-44 | IPR036640 |
| CDD | cd18577 | ABC_6TM_Pgp_ABCB1_D1_like | 131 | 448 | 5.0e-89 | - |
| Pfam | PF00664 | ABC transporter transmembrane region | 132 | 436 | 8.4e-56 | IPR011527 |
| ProSiteProfiles | PS50929 | ABC transporter integral membrane type-1 fused domain profile. | 132 | 452 | 38.636 | IPR011527 |
| SUPERFAMILY | SSF52540 | - | 480 | 720 | 5.6e-88 | IPR027417 |
| ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. | 486 | 722 | 25.604 | IPR003439 |
| CDD | cd03249 | ABC_MTABC3_MDL1_MDL2 | 487 | 720 | 1.1e-127 | - |
| Pfam | PF00005 | ABC transporter | 504 | 653 | 1.4e-36 | IPR003439 |
| SMART | SM00382 | - | 513 | 699 | 3.6e-19 | IPR003593 |
| ProSitePatterns | PS00211 | ABC transporters family signature. | 625 | 639 | - | IPR017871 |
| SUPERFAMILY | SSF90123 | - | 788 | 1101 | 1.0e-57 | IPR036640 |
| CDD | cd18578 | ABC_6TM_Pgp_ABCB1_D2_like | 790 | 1103 | 6.9e-101 | - |
| Pfam | PF00664 | ABC transporter transmembrane region | 800 | 1073 | 7.4e-58 | IPR011527 |
| ProSiteProfiles | PS50929 | ABC transporter integral membrane type-1 fused domain profile. | 801 | 1088 | 44.903 | IPR011527 |
| Gene3D | 3.40.50.300 | - | 1115 | 1372 | 7.9e-94 | - |
| SUPERFAMILY | SSF52540 | - | 1118 | 1364 | 2.2e-84 | IPR027417 |
| CDD | cd03249 | ABC_MTABC3_MDL1_MDL2 | 1124 | 1364 | 4.0e-132 | - |
| ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. | 1124 | 1363 | 26.117 | IPR003439 |
| Pfam | PF00005 | ABC transporter | 1143 | 1294 | 2.1e-33 | IPR003439 |
| SMART | SM00382 | - | 1151 | 1355 | 8.5e-17 | IPR003593 |
| ProSitePatterns | PS00211 | ABC transporters family signature. | 1266 | 1280 | - | IPR017871 |
InterPro assignment
| InterPro ID | InterPro description |
|---|---|
| IPR003439 | ABC transporter-like |
| IPR003593 | AAA+ ATPase domain |
| IPR011527 | ABC transporter type 1, transmembrane domain |
| IPR017871 | ABC transporter, conserved site |
| IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| IPR036640 | ABC transporter type 1, transmembrane domain superfamily |
| IPR039421 | Type I protein exporter |
Gene ontology (GO) assignment
| GO category | GO ID | GO description |
|---|---|---|
| molecular function | GO:0005524 | ATP binding |
| cellular component | GO:0016021 | integral component of membrane |
| molecular function | GO:0016887 | ATPase activity |
| molecular function | GO:0042626 | ATPase-coupled transmembrane transporter activity |
| biological process | GO:0055085 | transmembrane transport |
| Species | Accession |
|---|---|
| Danaus plexippus | DPOGS213261 |
| Heliconius melpomene | HMEL032178g1.t1 |
| Manduca sexta | XP_030028471.1 XP_030028472.1 |
| Plutella xylostella | g9119.t1 |
| Spodoptera frugiperda (corn) | GSSPFG00022700001.2-PA |
| Spodoptera frugiperda (rice) | SFRICE020481-PA |
| Acyrthosiphon pisum | XP_001947434.2 XP_016656026.1 |
| Aedes aegypti | AAEL010379-PA AAEL010379-PB AAEL010379-PC |
| Anopheles gambiae | AGAP005639-PA AGAP005639-PB |
| Apis mellifera | XP_006569045.1 XP_006569046.1 XP_016773577.1 |
| Drosophila melanogaster | FBpp0086914 |
| Tribolium castaneum | XP_008191266.1 XP_015833809.1 |
| Homo sapiens | NP_000918.2 NP_001335873.1 NP_001335875.1 |
| Mus musculus | XP_006503616.1 |