Position
| Chromosome | Chr12 |
| Start | 11596134 |
| End | 11614119 |
| Strand | - |
view in Gbrowse: Chr12:11596134..11614119
Most similar sequence in NCBI nr database
| Accession | Description | E-value | Score |
|---|---|---|---|
| XP_021203914.1 | LOW QUALITY PROTEIN: multidrug resistance-associated protein 1 | 0.0 | 2909 |
ORF sequence (4251 bp)
ATGACCATATACTTCCGGTTGCCGCAAACATTGGCTTTCCAACACATCATGAAAATATTGACGTTTACGTTGTCAGCAAGCTTAGTATGGCTTAACAAAAAACATGGAATGCGAGCTTCCGGCGTACTGTTTTTCTTCTGGTTACTGTTAGCTGTCATCGAAGTACCCAGGCTGTGGTGCAAAGCATTGGAATTGAAAATGAACTTCGTAAACGGAATACAATACGGATTTATTAGTCTTGCTATCCATTACGGACTGATAGTATTATTGTTAATATTGAATTGTTTCGCTGACGCAGCGCCACGTGATTCCGTGTACACGGATTCTCAGAACCAATGTCCCGAAAGATCTGCTGGTTTTCTAAGTCGTCTAACCTTCAGTTGGTTCGATTCTTTAGTACTAAAAGGATATCGTAAGGAATTTGAAGAAGGCGATGTGTGGGATTTGAATTATCAAGAATCTTCTTCAGAAGTCGTACCAAGATTTAAGAAATACTGGGAACAACCGGCAAATAGACGTAACTCATCAACAAAACACATAAAAGCAAAATTTCGAAGAAGATCAACTGATAGAACCATGAAAACTAATACTAAAAATCGAACTGTGTCAATATTACCAGCTCTTTGCTTTGCCTTCGGAGGACAGTTCATGTTTGGGACATTCCTGAAACTGCTGAGTGATATTTCCATTTTTTTATCACCACAACTGCTCAAGCTTCTTATAGGGTTTATAAGCAGCGATGAGCCAACATGGAGGGGCTACTTATATTCTTTCCTGTTCTTTGGTTGTGCCGCTCTTGAAACAACGCTGTTGAGTCATTACACTTTGAAAATGAACATTGTCGGAATGAGGATAAGAACAGCATTAACGAACGCTATTTACCAAATGGCTCTTCGCATGAACAATACGACGCGGAAGCAGTCGACAGTTGGTGAAATTATTAATCTGATGTCCGTGGATGCCCAAAGATTCGTCAGTTTGACAAGCACATTAAACATGATTTGGTCTGCGCCTTTTCAGATTGTGCTTGCTATTTATTTTTTGTGGGGCGTACTAGGTCCTTCTGTTCTCGCCGGATTGGCGGTTATGATTCTTTTAATTCCAATGAACGGTTTCATTGCTCGTATGGAAGAGAAACTGGAAATCAGATTAATGAAATTCAAAGATAACAGAATTAAAATCATGAATGAGGTGTTGAACGGAATTAAGGTCCTAAAAATGTATGCTTGGGAATTAAGTTTTCAAGGACAGATTGACCAAGTGAGAAATAAAGAACTTAATATACTGAAGAAAGTGATTTACTTAGATTCCCTGACGTCATTAACGTGGTCTGCGACACCATTTCTGGTTTCACTCACGTCTTTTGGGTGTTTTATTTTAGTAAATGATTCGGAGAGTTTGGATTCAAAGAAATTATTTGTGGCCTTATCTCTATTCAACATATTACGTTATCCATTAATGATGCTGCCAAACACAATATCAAATATCGTTCAAACTTCCGTTAGCATAAAACGTTTAAATAAATTTTTGAATTCAACGGTTTTAGATTTAGAATCAATCGAACATGACCCTCAATATTCCTATCCGATAACTGTGGAAAACGGACACTTCTCGTGGGAAGGTCAAGATTCTAGTACGGTGTTGAGAAATATAAATTTGCGTGTGCCCCGAGGTTCTTTGGTGGCAATAGTCGGTGCTGTGGGCGCCGGGAAGAGCTCGTTACTGTCCGCACTTTTGGGCGAGATGACTAAGGTGTCGGGACGTGTCAACGTTCACGGTACAATAGCATACGTGTCACAAGAGCCATGGATACAGAATGCCACATTGAAAGATAACATTCTCTTCGGGAAGCCGTTTAATAAATACAAATATAAGAATGTACTAAACGCCTGTACTCTTGTGCAAGACTTGGAAATATTTCCCGGAGGAGATCTAACTGAGATAGGTGAAAAAGGTATAAACTTATCGGGCGGTCAGAAGCAGCGCGTGTCGCTGGCGCGCGCCGTGTACCACGAGGCGGACAACTACCTGCTGGACGACCCGCTCAGCGCCGTGGACTCGCACGTCGGCAAGCACATCTTCGACAAGGTCATCGGGCCCGCCGGCCTGCTCAAGGACAGGACGCGCGTCTGGGTCACGCACAACGTGTCCTACCTCGCGCAGACCGACCTGGTCGTCGTGCTGCGCGACGGACAGGTCTCCGAGGCCGGCTCCTACCAGCACCTGCTCGAGAAGAAGGGCGCCTTTGCTGACTTCCTGCTTCATCATCTAAGCGATGCAGAACGGTCATCAGTCGAATCTGTCAGAAAACAAGACCACGAATACAGATGCTCAAGGACAGAATCCCACCAGAATTTACAAAGAATTCGTTTACATTCCGAGAGCAACTCAGAAGCAGAGGACCGATCAGGAAAACTAGCTATCAGCTTTAAAAGAAGTATCGAAGAAATTATTTTAAATAAATCCGCCGAGCACGTTAGTTATACTGAAAAAGAGAAATCTGAAAGGGGCAGTGTTTCGTGGATGGTTTACAAGCACTACTTGAAAAACATCGGCGTACTGGCCGCAGCAGCTACTATACTAATGAACGTGGTTCTACAGCTCTTTCATATCGGTTCGAGCTATTGGTTGGCAGAATGGTCCGACAACGAGAACGAAGTTGTTAACAGTACTATGAATTTGAACCAGCGGAACAAGTACCTCGCAGTATACGCTGGCCTCGGTATGGGACAAGCGATATCGTCATTTCTAGCCGACTTGATACCATACTTGGCGTGCTGGCGAGCTGCGAAGGTCATCCACGAACTGTTACTGGACAATGTGTTAAAGACGCCGTTGCATTTTTTCGAAGTCACGCCTATTGGCAGAATACTGTCAAGATTCTCTAAAGATATTGAAATTATTGACTCTATGCTACCTTCTCAATTAATCAATGGGGTGTATTGCGTCTTCGAACTCATTGGCATTTTATTCGTGATAAGCTTGTCGACGCCATCATTCTTAGCAATAGTTGTACCAGTAGGTCTAGTGTACTATGTAATACAACGGTTCTACGTGGCTACGTCTCGTCAGCTCAAGCGGCTAGAGTCCATAGCTCGCTCGCCGATATTCTCACACTTCGGCGAAACGATCAGTGGAGCAGCCACCATTCGCGCTTTCAACGTAACCGAGAGGTTTATTGAAGAATCAAATGAAAAGTTAGATCGCAACCTCGCTTATTGCTATGCGATTGTAGTAGGAAAGCGATGGCTTGGTTTCCGATTAGAATTCATTGGAAACTTCATATTATTTTTCGCTGCAATGTTTGCTGTTCTCAGCAGAGATACTATAAGCTCGGGTCTCGTGGGACTTTCCTTAACCTACGCTATGCAGGTAACTGCATCGTTGAATTGGCTTGTTCGGCTAGCTTCTGAAATTGAAAGTAATATTGTAGCTGTAGAACGGATAAAAGAATACTCTGAGAAAAATAAGGAAGCTGCGTGGAACTTAGGGAAAGGGCCCGGCGTGACGTGGCCCGAGACGGGAGCGCTACAGCTGGAGCAGCTGACGCTGGAGTACCGCCCCGGCGAGCCGGCGCTGCGTGACGTCACGTGCACGGTCGCGCCGCGCGACAAGCTCGGCATCGTGGGACGCACCGGCGCCGGCAAGTCTACTCTCACGCTCGGGCTCTTCAGGATCGTGGAGGCAGCCGCCGGACGCATCCTGATCGACGGCGTCGACATCGCGACCCTCGGGCTGCACCAGCTGCGGTCGCGCATCACCATCATCCCGCAGGAGCCGATCCTGTTCTCGGGCACGCTGCGCACCAACCTGGACCCGTTCGAGGCGTATAGCGACGAGGAGATCTGGCGCGCGCTGGAACACGCCCACCTCCGTGCCTTCGTGCAGGGGCTGCCGGCCGGGCTGCGGCACGAGGTGGCGGAGGGCGGCGAGAACCTGTCGGTGGGACAGCGCCAGCTCGTGTGCCTGGCGCGCGCGCTGCTACGCAAGACGCCGCTGCTGGTGCTGGACGAGGCCACCGCGGCCGTCGACCTCGAGACTGACGACCTCATCCAGAAGACGATCCGCTCGGAGTTCGCGTCGTGCACGGTGCTCACTATCGCGCACCGCCTCAACACCATCATGGACTCCACCAAAGTGATGGTGCTCGACCGCGGGCAGCTCGTAGAATATGCGGCCCCTCAACAACTACTTAACGATAAAAACTCCATTTTCTACTCCTTAGCAAAAGATGCTGGAATTGTCAGTTGA
Protein sequence (1416 aa)
MTIYFRLPQTLAFQHIMKILTFTLSASLVWLNKKHGMRASGVLFFFWLLLAVIEVPRLWCKALELKMNFVNGIQYGFISLAIHYGLIVLLLILNCFADAAPRDSVYTDSQNQCPERSAGFLSRLTFSWFDSLVLKGYRKEFEEGDVWDLNYQESSSEVVPRFKKYWEQPANRRNSSTKHIKAKFRRRSTDRTMKTNTKNRTVSILPALCFAFGGQFMFGTFLKLLSDISIFLSPQLLKLLIGFISSDEPTWRGYLYSFLFFGCAALETTLLSHYTLKMNIVGMRIRTALTNAIYQMALRMNNTTRKQSTVGEIINLMSVDAQRFVSLTSTLNMIWSAPFQIVLAIYFLWGVLGPSVLAGLAVMILLIPMNGFIARMEEKLEIRLMKFKDNRIKIMNEVLNGIKVLKMYAWELSFQGQIDQVRNKELNILKKVIYLDSLTSLTWSATPFLVSLTSFGCFILVNDSESLDSKKLFVALSLFNILRYPLMMLPNTISNIVQTSVSIKRLNKFLNSTVLDLESIEHDPQYSYPITVENGHFSWEGQDSSTVLRNINLRVPRGSLVAIVGAVGAGKSSLLSALLGEMTKVSGRVNVHGTIAYVSQEPWIQNATLKDNILFGKPFNKYKYKNVLNACTLVQDLEIFPGGDLTEIGEKGINLSGGQKQRVSLARAVYHEADNYLLDDPLSAVDSHVGKHIFDKVIGPAGLLKDRTRVWVTHNVSYLAQTDLVVVLRDGQVSEAGSYQHLLEKKGAFADFLLHHLSDAERSSVESVRKQDHEYRCSRTESHQNLQRIRLHSESNSEAEDRSGKLAISFKRSIEEIILNKSAEHVSYTEKEKSERGSVSWMVYKHYLKNIGVLAAAATILMNVVLQLFHIGSSYWLAEWSDNENEVVNSTMNLNQRNKYLAVYAGLGMGQAISSFLADLIPYLACWRAAKVIHELLLDNVLKTPLHFFEVTPIGRILSRFSKDIEIIDSMLPSQLINGVYCVFELIGILFVISLSTPSFLAIVVPVGLVYYVIQRFYVATSRQLKRLESIARSPIFSHFGETISGAATIRAFNVTERFIEESNEKLDRNLAYCYAIVVGKRWLGFRLEFIGNFILFFAAMFAVLSRDTISSGLVGLSLTYAMQVTASLNWLVRLASEIESNIVAVERIKEYSEKNKEAAWNLGKGPGVTWPETGALQLEQLTLEYRPGEPALRDVTCTVAPRDKLGIVGRTGAGKSTLTLGLFRIVEAAAGRILIDGVDIATLGLHQLRSRITIIPQEPILFSGTLRTNLDPFEAYSDEEIWRALEHAHLRAFVQGLPAGLRHEVAEGGENLSVGQRQLVCLARALLRKTPLLVLDEATAAVDLETDDLIQKTIRSEFASCTVLTIAHRLNTIMDSTKVMVLDRGQLVEYAAPQQLLNDKNSIFYSLAKDAGIVS
Corresponding sequences in KAIKObase version 1
BMgn010332Domains and motifs
| Database | ID | Description | Start | End | Evalue | InterPro ID |
|---|---|---|---|---|---|---|
| PANTHER | PTHR24223 | - | 17 | 1415 | 0.0 | - |
| PANTHER | PTHR24223:SF350 | - | 17 | 1415 | 0.0 | - |
| TIGRFAM | TIGR00957 | MRP_assoc_pro: multi drug resistance-associated protein (MRP) | 20 | 1414 | 0.0 | IPR005292 |
| Gene3D | 1.20.1560.10 | - | 209 | 513 | 2.0e-20 | IPR036640 |
| SUPERFAMILY | SSF90123 | - | 211 | 511 | 1.4e-37 | IPR036640 |
| Pfam | PF00664 | ABC transporter transmembrane region | 217 | 486 | 1.9e-36 | IPR011527 |
| CDD | cd18595 | ABC_6TM_MRP1_2_3_6_D1_like | 218 | 506 | 1.3e-149 | - |
| ProSiteProfiles | PS50929 | ABC transporter integral membrane type-1 fused domain profile. | 218 | 498 | 36.21 | IPR011527 |
| SUPERFAMILY | SSF52540 | - | 524 | 753 | 2.6e-58 | IPR027417 |
| Gene3D | 3.40.50.300 | - | 528 | 761 | 4.9e-72 | - |
| CDD | cd03250 | ABCC_MRP_domain1 | 530 | 732 | 2.1e-119 | - |
| ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. | 530 | 755 | 22.616 | IPR003439 |
| Pfam | PF00005 | ABC transporter | 548 | 682 | 5.6e-20 | IPR003439 |
| SMART | SM00382 | - | 557 | 823 | 3.6e-05 | IPR003593 |
| ProSitePatterns | PS00211 | ABC transporters family signature. | 655 | 669 | - | IPR017871 |
| Gene3D | 1.20.1560.10 | - | 820 | 1159 | 4.7e-46 | IPR036640 |
| ProSiteProfiles | PS50929 | ABC transporter integral membrane type-1 fused domain profile. | 857 | 1141 | 41.103 | IPR011527 |
| SUPERFAMILY | SSF90123 | - | 857 | 1154 | 8.5e-58 | IPR036640 |
| CDD | cd18603 | ABC_6TM_MRP1_2_3_6_D2_like | 859 | 1153 | 4.8e-151 | - |
| Pfam | PF00664 | ABC transporter transmembrane region | 859 | 1128 | 1.3e-38 | IPR011527 |
| Gene3D | 3.40.50.300 | - | 1164 | 1410 | 2.4e-84 | - |
| SUPERFAMILY | SSF52540 | - | 1169 | 1408 | 1.1e-68 | IPR027417 |
| CDD | cd03244 | ABCC_MRP_domain2 | 1175 | 1394 | 4.3e-126 | - |
| ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. | 1177 | 1410 | 18.161 | IPR003439 |
| Pfam | PF00005 | ABC transporter | 1193 | 1341 | 3.3e-28 | IPR003439 |
| SMART | SM00382 | - | 1202 | 1387 | 1.8e-11 | IPR003593 |
| ProSitePatterns | PS00211 | ABC transporters family signature. | 1313 | 1327 | - | IPR017871 |
InterPro assignment
| InterPro ID | InterPro description |
|---|---|
| IPR003439 | ABC transporter-like |
| IPR003593 | AAA+ ATPase domain |
| IPR005292 | Multi drug resistance-associated protein |
| IPR011527 | ABC transporter type 1, transmembrane domain |
| IPR017871 | ABC transporter, conserved site |
| IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| IPR036640 | ABC transporter type 1, transmembrane domain superfamily |
Gene ontology (GO) assignment
| GO category | GO ID | GO description |
|---|---|---|
| molecular function | GO:0005524 | ATP binding |
| cellular component | GO:0016021 | integral component of membrane |
| molecular function | GO:0016887 | ATPase activity |
| molecular function | GO:0022857 | transmembrane transporter activity |
| molecular function | GO:0042626 | ATPase-coupled transmembrane transporter activity |
| biological process | GO:0055085 | transmembrane transport |
| Species | Accession |
|---|---|
| Danaus plexippus | - |
| Heliconius melpomene | - |
| Manduca sexta | - |
| Plutella xylostella | - |
| Spodoptera frugiperda (corn) | GSSPFG00026400001.2-PA GSSPFG00030433001-PA |
| Spodoptera frugiperda (rice) | - |
| Acyrthosiphon pisum | - |
| Aedes aegypti | - |
| Anopheles gambiae | - |
| Apis mellifera | - |
| Drosophila melanogaster | - |
| Tribolium castaneum | - |
| Homo sapiens | - |
| Mus musculus | - |
The expression data was obtained from RNA-seq data of ten tissues/locations.
Three replicates were sequenced from each tissue/location.
The Y axis is the abundance value (transcripts per million (TPM))
The X axis is the tissues/locations with the following abbreviations:
ASG: anterior silk gland; FB: fat body; MG: midgut;
MSG_A: middle silk gland (anterior); MSG_M: middle silk gland (middle); MSG_P: middle silk gland (posterior);
MT: Malpighian tubules; OV: ovary; PSG: posterior silk gland; TT: testis
For more details, please refer to the article "Reference transcriptome data in silkworm Bombyx mori" (Yokoi et al., 2019).
Expression data (TPM) can be obtained from National Bioscience Database Center.
Expression data of KWMTBOMO07382:
Expression data of alternative splicing isoform(s) of KWMTBOMO07382:
MSTRG.4003.1 (position: Chr12:11595173..11597661)
MSTRG.4003.3 (position: Chr12:11596147..11597746)
The expression data was obtained from RNA-seq data of ten tissues/locations.
Three replicates were sequenced from each tissue/location.
The Y axis is the abundance value with log10 conversion (value of transcripts per million (TPM) plus 1 is used to avoid negative output)
The X axis is the tissues/locations with the following abbreviations:
ASG: anterior silk gland; FB: fat body; MG: midgut;
MSG_A: middle silk gland (anterior); MSG_M: middle silk gland (middle); MSG_P: middle silk gland (posterior);
MT: Malpighian tubules; OV: ovary; PSG: posterior silk gland; TT: testis
For more details, please refer to the article "Reference transcriptome data in silkworm Bombyx mori" (Yokoi et al., 2019).
Expression data (TPM) can be obtained from National Bioscience Database Center.
Expression data of KWMTBOMO07382:
Expression data of alternative splicing isoform(s) of KWMTBOMO07382:
MSTRG.4003.1 (position: Chr12:11595173..11597661)
MSTRG.4003.3 (position: Chr12:11596147..11597746)