Position
| Chromosome | chr8 |
| Start | 9998245 |
| End | 10016383 |
| Strand | + |
view in Gbrowse: chr8:9998245..10016383
Most similar sequence in NCBI nr database
| Accession | Description | E-value | Score |
|---|
| XP_012550859.1 | ATP-binding cassette transporter subfamily B isoform X1 | 0.0 | 1749 |
ORF sequence (2553 bp)
ATGATGAAGTATTGTCCTCCAAATGTGACACTTGGAGAGATATGGGTGGATCACGGCATATCACAATGTTTCATGGAGACCGTATCTGCTGTGTTCATAGGTGGATTCCTATTGGTCTTGGGAACCACACAAATTGTTATTTACAAAAGACATGCCACTGAGGTGATGGATGTCCGATCATCGAAGCTTTTTGGAGTTCAGATGTTTTTTACTCTTTTAGTACCAGTGTTGGCTGTAATAAGGTTTCTGTTACAAGCATTATTGTTCAAAAGTGGTTGTGTGTATGGTTATATGGTAGTTGCATTAACAGTTACTCTGGTAGTATTTCCATTGTCGGCCTACTTAGCGATCCTCGAGAGGAGGTTCTTATTACCGTCCGTGCCTCCTAGAGGTCACGGTTTTGTACTCTTGGTTTTTTGGGCTATGATATTCGTATCGGAGAATTTATCATTTTTAAATATCAACAAAGAAGGATGGTGGTGGCACTTGAAAAATCTTCAAGATCGCCTCGAAATGTCATTGTTCGTCGGTCGTTACGTGTCGTGTATGATAATGTTCGTGCTCGGTATGAAGGCGCCGGGCATCATGCACCACTTCGACTACTTAGAGGACGAACACGAAGGCCGAAGGAATATACAGCCACGCGATGACAACAGATCGACGTTCAGAAATGTGTTTACGAAATTGCGCACACTCCTACCGTTCCTGTGGCCGAAGAAGAATTTCATCCTCCAACTCTATGTGCTCATATGTATACTGGCTCTCATTGCTGGAAGAGCTATCAATCTATACGTCCCTATATACAACAGGCTGATATTTAACAGCATATCGGAACCGCCTCTCTCCTTCCGCTGGGATCTGGTATTGATATATGTGTTTTTCAAGTTCCTCCAAGGAGGGGGTACCGGCGGAATGGGTTTATTGAATAATATGCGTTCGTTTTTGTGGATCAAGGTCCAACAATACACCACAAGAGAGTTGGAGCTGGAACTGTTCAAGCATCTCCATGACTTGCCTTTACGCTGGCATTTGTCTCGCAAAACCGGAGAAGTCCTCAGGGTGATGGACCGAGGAACGGATTCTATAAACAATCTCCTCTCGTACATTCTGTTCTCTATCACTCCAACGCTGGTCGATATCTTGGTGGCAGTCATCTATTTTGTCACGGCGTTCAATATTTGGTTCGGACTGATCGTTTTTACTACAATGATCCTGTATATTATCGCAACAATAGCCGTGACGGAATGGCGCACGAAGTTCCAACGTCGCATGAATCTCGCCGACAACGAGCAGAAGGCTCGCTCGGTCGACTCTCTGTTGAACTACGAGACTGTTAAATATTACGGAGCGGAATCTTATGAAGTGATGTCTTATAGAGAAGCCATCCTTAATTATCAGAAAGAAGAGTTTAAATCATTGTTCACATTAAACATTTTGAACACCATTCAAAATATCATCATCTGCAGCGGCTTACTTGCTGGTTCGTTGCTCTGCGTGTCGTTGGTGGTGAAGACGGCTGAATTCACTGTCGGTGACTACGCTTTGTTCGCGTCGTACATAGTGCAGCTTTACGTTCCCTTGAATTGGTTCGGAACATATTACAGAGCTATACAGAAGAATTTCGTGGACATGGAGAACATGTTCGACCTGCTGAGGGTGGATACGGACGTGCGCGACGCGGCCGGGGCGCCCGAGCTGGTGGTGCGGCGCGGCGGAGTCGAGTTCAAGCACGTGTCCTTCGGATACGGCTCCGAGAGGCTCGTCCTTAACAACATCAGTTTTAAAATCGCCCCCGGAAGCACCGTTGCATTGGTCGGGCCCAGCGGCGCGGGAAAATCGACGATAATGCGTCTGTTATTCCGTTTTTACGACGTGAACGAGGGCGCCGTGCTGGTGGACGAGCAGGACGTGCGCACCGTCACGCAGGCCTCGCTGCGCGCCAACATCGGCGTCGTGCCGCAGGACACGGTGCTCTTCAACAACACCGTTAGATACAACATTCAATACGGAAGATTGAACGCGCCCGCCGCTGATATAATATCTGCCGCCAAGAACGCGGACATTCACGACCGAATACTGACGTTTCCCGACGCTTACGACACGCAGGTTGGAGAAAGGGGCCTTAGGCTGAGCGGTGGCGAAAAGCAAAGAATAGCTATTGCACGAACGATCTTAAAAGATCCCGCCATTGTCCTGCTCGATGAAGCTACTTCTGCGCTAGACACGAACACAGAAAGAAATATTCAAGCCGCGTTGGCACGAGTGTGCGCAAACAGAACTACCCTTATAATTGCACACAGGCTCTCAACGATCATTCATGCCGACGAAATACTGGTCCTTAAGGACGGTGAGATTATCGAACGTGGAAACCATGAAGCCCTCCTAGCGCAGGCCGGGTTCTATGCGTCCATGTGGCAACAGCAACTCGAGAATCGAAACAGCAACGGTAACAACGATGATGACGTCAGCGGCGGCGAAGGGAACAACAACCAGAGGAGCCAAATCGTCGCGCCCGTGTTCGGTCACGGCCATGGTCATGGGCATGGTCATTAA
Protein sequence (850 aa)
MMKYCPPNVTLGEIWVDHGISQCFMETVSAVFIGGFLLVLGTTQIVIYKRHATEVMDVRSSKLFGVQMFFTLLVPVLAVIRFLLQALLFKSGCVYGYMVVALTVTLVVFPLSAYLAILERRFLLPSVPPRGHGFVLLVFWAMIFVSENLSFLNINKEGWWWHLKNLQDRLEMSLFVGRYVSCMIMFVLGMKAPGIMHHFDYLEDEHEGRRNIQPRDDNRSTFRNVFTKLRTLLPFLWPKKNFILQLYVLICILALIAGRAINLYVPIYNRLIFNSISEPPLSFRWDLVLIYVFFKFLQGGGTGGMGLLNNMRSFLWIKVQQYTTRELELELFKHLHDLPLRWHLSRKTGEVLRVMDRGTDSINNLLSYILFSITPTLVDILVAVIYFVTAFNIWFGLIVFTTMILYIIATIAVTEWRTKFQRRMNLADNEQKARSVDSLLNYETVKYYGAESYEVMSYREAILNYQKEEFKSLFTLNILNTIQNIIICSGLLAGSLLCVSLVVKTAEFTVGDYALFASYIVQLYVPLNWFGTYYRAIQKNFVDMENMFDLLRVDTDVRDAAGAPELVVRRGGVEFKHVSFGYGSERLVLNNISFKIAPGSTVALVGPSGAGKSTIMRLLFRFYDVNEGAVLVDEQDVRTVTQASLRANIGVVPQDTVLFNNTVRYNIQYGRLNAPAADIISAAKNADIHDRILTFPDAYDTQVGERGLRLSGGEKQRIAIARTILKDPAIVLLDEATSALDTNTERNIQAALARVCANRTTLIIAHRLSTIIHADEILVLKDGEIIERGNHEALLAQAGFYASMWQQQLENRNSNGNNDDDVSGGEGNNNQRSQIVAPVFGHGHGHGHGH
Domains and motifs
| Database | ID | Description | Start | End | Evalue | InterPro ID |
|---|
| Pfam | PF16185 | Mitochondrial ABC-transporter N-terminal five TM region |
3 | 238 | 7.4e-85 |
IPR032410 |
| PANTHER | PTHR24221 | - |
205 | 811 | 0.0 |
IPR039421 |
| PANTHER | PTHR24221:SF187 | - |
205 | 811 | 0.0 |
- |
| SUPERFAMILY | SSF90123 | - |
230 | 552 | 4.1e-51 |
IPR036640 |
| Gene3D | 1.20.1560.10 | - |
235 | 562 | 5.6e-109 |
IPR036640 |
| Pfam | PF00664 | ABC transporter transmembrane region |
248 | 526 | 5.4e-37 |
IPR011527 |
| ProSiteProfiles | PS50929 | ABC transporter integral membrane type-1 fused domain profile. |
249 | 539 | 35.18 |
IPR011527 |
| CDD | cd18581 | ABC_6TM_ABCB6 |
251 | 547 | 1.7e-169 |
- |
| Gene3D | 3.40.50.300 | - |
563 | 824 | 3.1e-92 |
- |
| SUPERFAMILY | SSF52540 | - |
565 | 808 | 9.5e-91 |
IPR027417 |
| CDD | cd03253 | ABCC_ATM1_transporter |
573 | 808 | 1.5e-153 |
- |
| ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. |
573 | 807 | 22.816 |
IPR003439 |
| Pfam | PF00005 | ABC transporter |
589 | 738 | 2.6e-34 |
IPR003439 |
| SMART | SM00382 | - |
598 | 784 | 2.3e-15 |
IPR003593 |
| ProSitePatterns | PS00211 | ABC transporters family signature. |
710 | 724 | - |
IPR017871 |
InterPro assignment
| InterPro ID | InterPro description |
|---|
| IPR003439 | ABC transporter-like |
| IPR003593 | AAA+ ATPase domain |
| IPR011527 | ABC transporter type 1, transmembrane domain |
| IPR017871 | ABC transporter, conserved site |
| IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| IPR032410 | Mitochondrial ABC-transporter, N-terminal five TM domain |
| IPR036640 | ABC transporter type 1, transmembrane domain superfamily |
| IPR039421 | Type I protein exporter |
Gene ontology (GO) assignment
| GO category | GO ID | GO description |
|---|
| molecular function | GO:0005524 | ATP binding |
| cellular component | GO:0016021 | integral component of membrane |
| molecular function | GO:0016887 | ATPase activity |
| molecular function | GO:0042626 | ATPase-coupled transmembrane transporter activity |
| biological process | GO:0055085 | transmembrane transport |